CAS 614-05-1

Thiazolium, 3-[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, hydrochloride (1:1:1)

Description:

Thiazolium, 3-[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, hydrochloride (1:1:1) is a chemical compound characterized by its thiazolium core, which is a five-membered heterocyclic ring containing sulfur and nitrogen. This compound features a pyrimidinyl substituent, contributing to its biological activity and potential pharmacological properties. The presence of hydroxyl and methyl groups enhances its solubility and reactivity. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, making it suitable for various applications in medicinal chemistry and biochemistry. The compound may exhibit antimicrobial or antifungal properties, which are common in thiazolium derivatives. Its molecular structure allows for interactions with biological targets, potentially influencing enzyme activity or cellular processes. Overall, this compound represents a class of thiazolium derivatives that are of interest for their therapeutic potential and utility in research.

Formula: C₁₂H₁₆N₃O₂S·ClH·Cl

InChI: InChI=1S/C12H15N3O2S.2ClH/c1-8-11(3-4-16)18-7-15(8)6-10-5-13-9(2)14-12(10)17;;/h5,7,16H,3-4,6H2,1-2H3;2*1H

InChI key: InChIKey=HGYQKVVWNZFPJS-UHFFFAOYSA-N

SMILES: C([N+]=1C(C)=C(CCO)SC1)C=2C(=O)NC(C)=NC2.[Cl-].Cl

Synonyms:

• 5-(2-Hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methylthiazolium chloride, hydrochloride
• 5-(2-Hydroxyethyl)-3-[(4-hydroxy-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium chloride hydrochloride (1:1:1)
• Hydroxythiamine chloride hydrochloride
• Oxythiamine chloride hydrochloride
• Thiazolium, 3-[(1,4-dihydro-2-methyl-4-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
• Thiazolium, 3-[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, hydrochloride (1:1:1)
• Thiazolium, 5-(2-Hydroxyethyl)-3-[(4-Hydroxy-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-, Chloride, Hydrochloride (1:1:1)
• Thiazolium, 5-(2-hydroxyethyl)-3-(4-hydroxy-2-methyl-5-pyrimidylmethyl)-4-methyl-, chloride, -HCl
• Thiazolium, 5-(2-hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methyl-, chloride, hydrochloride
• Thiazolium, 5-(2-hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methyl-, chloride, monohydrochloride
• 5-[[5-(2-hydroxyethyl)-4-methyl-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride
• Oxametholone Hydrochloride
• OXYTHIAMINE HCL
• hyl)-4-methyl-,chloride,monohydrochloride
• hydroxythiaminechloridehydrochloride
• 5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride
• OXYTHIAMINE CHLORIDE HCL CRYSTALLINE
• 5-(2-HYDROXYETHYL)-3-(4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL)-4-METHYLTHIAZOLIUM CHLORIDE
• 5-(2-Hydroxyethyl)-4-methyl-3-[(2-methyl-6-oxo-1,6-dihydro-5-pyrimidinyl)methyl]-1,3-thiazol-3-ium chloride hydrochloride (1:1:1)
• OXYTHIAMINE HYDROCHLORIDE

Oxythiamine · HCl

CAS: 614-05-1

Thiamine antagonist and inhibitor of saccharomyces cerevisiae transketolase. Raïs et al. indicated that oxythiamine inhibits the growth of Ehrlich’s tumor cells.

Formula: C₁₂H₁₆ClN₃O₂S·HCl

Purity: 95%

Color and Shape: White

Molecular weight: 338.26

Ref: 01-4002126

Oxythiamine, HCl

CAS: 614-05-1

Formula: C₁₂H₁₇Cl₂N₃O₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 338.2533

Ref: IN-DA00E9HW

Oxythiamine chloride hydrochloride

CAS: 614-05-1

Formula: C₁₂H₁₆ClN₃O₂S·HCl

Purity: ≥ 95.0%

Color and Shape: White to almost white powder

Molecular weight: 339.26

Ref: 7W-GV2536

Oxythiamine Chloride HCl

CAS: 614-05-1

Formula: C₁₂H₁₆N₃O₂S·Cl·HCl

Molecular weight: 266.34 35.45 36.46

Ref: 4Z-T-8425

Oxythiamine Hydrochloride

Controlled Product

CAS: 614-05-1

Stability Hygroscopic
Applications Oxythiamine HCl (cas# 136-16-3) is a useful research chemical.

Formula: C₁₂H₁₅N₃O₂S·HCl

Color and Shape: Neat

Molecular weight: 301.79

Ref: TR-O878508

Oxythiamine chloride hydrochloride

CAS: 614-05-1

Oxythiamine chloride hydrochloride is an inhibitor of thiamine-dependent enzymes. It is used in cell factor binding and as a biological control for studies involving the effects of thiamine-dependent reactions. The compound has been shown to inhibit enzyme activities in plants and animal tissues, including those that are involved in energy metabolism. Oxythiamine chloride hydrochloride also has inhibitory properties that may be due to its ability to bind to integrin receptors on the cell surface or to its ability to inhibit DNA synthesis by binding to nuclear DNA.

Formula: C₁₂H₁₆ClN₃O₂S•HCl

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 338.25 g/mol

Ref: 3D-FO111176

Oxythiamine chloride HCl

CAS: 614-05-1

Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.

Formula: C₁₂H₁₇Cl₂N₃O₂S

Color and Shape: Solid

Molecular weight: 338.25

Ref: TM-T71783

Oxythiamine Hydrochloride

CAS: 614-05-1

Formula: C₁₂H₁₆N₃O₂SClHCl

Molecular weight: 266.34 : 35.45 : 36.46

Ref: ST-EA-CP-T2025