CAS 614-69-7

2-Methylphenyl isothiocyanate

Description:

2-Methylphenyl isothiocyanate, also known as o-tolyl isothiocyanate, is an organic compound characterized by the presence of an isothiocyanate functional group attached to a methyl-substituted phenyl ring. Its molecular formula is C8H9NIS, and it features a distinctive structure that includes a phenyl ring with a methyl group at the ortho position relative to the isothiocyanate group. This compound is typically a colorless to pale yellow liquid with a pungent odor, reminiscent of mustard oil, due to the presence of the isothiocyanate group. It is known for its reactivity, particularly in nucleophilic substitution reactions, and can act as a potent electrophile. 2-Methylphenyl isothiocyanate is utilized in various applications, including organic synthesis and as a reagent in chemical research. Additionally, it has been studied for its potential biological activities, including antimicrobial and anticancer properties. However, it should be handled with care due to its irritant nature and potential toxicity.

Formula: C₈H₇NS

InChI: InChI=1S/C8H7NS/c1-7-4-2-3-5-8(7)9-6-10/h2-5H,1H3

InChI key: InChIKey=JYKYYPPZLPVIBY-UHFFFAOYSA-N

SMILES: N(=C=S)C1=C(C)C=CC=C1

Synonyms:

• 1-Isothiocyanato-2-methylbenzene
• 2-Methylphenyl isothiocyanate
• 2-Tolyl isothiocyanate
• Benzene, 1-isothiocyanato-2-methyl-
• Isothiocyanic acid, o-tolyl ester
• NSC 220230
• o-Methylphenyl isothiocyanate
• o-Tolyl isothiocyanate

o-Tolyl Isothiocyanate

CAS: 614-69-7

Formula: C₈H₇NS

Purity: >99.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 149.21

Ref: 3B-I0458

o-Tolyl isothiocyanate, 98%

CAS: 614-69-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₇NS

Purity: 98%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 149.21

Ref: 02-B22845

1-isothiocyanato-2-methylbenzene

CAS: 614-69-7

Formula: C₈H₇NS

Purity: 98%

Color and Shape: Liquid

Molecular weight: 149.2129

Ref: IN-DA00IKIS

2-methylphenyl isothiocyanate

CAS: 614-69-7

2-methylphenyl isothiocyanate

Purity: 98%

Color and Shape: Yellow-Orange Liquid

Molecular weight: 149.21g/mol

Ref: 54-OR28816

2-Tolylisothiocyanate

CAS: 614-69-7

Formula: C₈H₇NS

Purity: 99.0%

Color and Shape: Liquid, Yellow/orange liquid

Molecular weight: 149.21

Ref: 10-F001280

o-Tolyl Isothiocyanate

CAS: 614-69-7

O-Tolyl isothiocyanate (OTIC) is a chemical compound that has anti-cancer properties. OTIC inhibits the growth of cancer cells by causing apoptosis, or programmed cell death. OTIC also blocks the production of prostaglandins, which are proinflammatory molecules that mediate pain and inflammation. OTIC has been shown to inhibit cox-2, an enzyme involved in inflammatory processes. The inhibition of cox-2 by OTIC may be responsible for its anticancer activity. O-Tolyl isothiocyanate also inhibits pancreatic lipase, which plays a key role in fat digestion and may have implications for weight loss and diabetes treatment. OTIC has also been used as a natural preservative because it inhibits the growth of bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus. In addition, OTIC is an inhibitor of size-exclusion chromatography on proteins, which

Formula: C₈H₇NS

Purity: Min. 95%

Molecular weight: 149.21 g/mol

Ref: 3D-AAA61469