CAS 614-96-0

5-Methylindole

Description:

5-Methylindole, with the CAS number 614-96-0, is an organic compound that belongs to the indole family, characterized by a bicyclic structure consisting of a benzene ring fused to a pyrrole ring. This compound features a methyl group attached to the fifth position of the indole structure, which influences its chemical properties and reactivity. 5-Methylindole is typically a colorless to pale yellow liquid or solid, depending on its purity and form. It is known for its aromatic properties and is often used in organic synthesis and as an intermediate in the production of various pharmaceuticals and agrochemicals. The compound exhibits moderate solubility in organic solvents and is relatively stable under standard conditions. Additionally, 5-Methylindole can participate in various chemical reactions, including electrophilic substitutions and cyclizations, making it a valuable building block in synthetic organic chemistry. Its biological activity has also been studied, particularly in relation to its potential effects on human health and its role in the metabolism of certain compounds.

Formula: C₉H₉N

InChI: InChI=1S/C9H9N/c1-7-2-3-9-8(6-7)4-5-10-9/h2-6,10H,1H3

InChI key: InChIKey=YPKBCLZFIYBSHK-UHFFFAOYSA-N

SMILES: CC=1C=C2C(=CC1)NC=C2

Synonyms:

• 1H-Indole, 5-methyl-
• 5-Methylindol
• 5-methyl-1H-indole
• Akos Jy208295
• Indole, 5-methyl-
• NSC 522562
• 5-Methylindole

5-Methylindole

CAS: 614-96-0

Formula: C₉H₉N

Purity: >99.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 131.18

Ref: 3B-M0348

5-Methylindole, 99%

CAS: 614-96-0

5-Methylindole is used as reactant for preparation of pharmaceutically active 2-oxo-1-pyrrolidine analogues, potential anticancer immunomodulators, IL2-inducible T-cell kinase (ITK) inhibitors and CRTh2 antagonists. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar

Formula: C₉H₉N

Purity: 99%

Color and Shape: White to cream to pale yellow, Crystals or powder or crystalline powder

Molecular weight: 131.18

Ref: 02-L06893

5-Methylindole

CAS: 614-96-0

Formula: C₉H₉N

Purity: 98%

Color and Shape: Solid

Molecular weight: 131.1745

Ref: IN-DA003MW6

5-Methylindole

CAS: 614-96-0

Formula: C₉H₉N

Molecular weight: 131.18

Ref: 7W-GK9066

5-Methylindole

CAS: 614-96-0

5-Methylindole is a indole that inhibits a variety of kinases in bacteria and animals and Tryptophan synthase in plants for leukaemia and Alzheimer's disease.

Formula: C₉H₉N

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 131.17

Ref: TM-TYD-00517

5-Methyl-1H-indole

CAS: 614-96-0

5-Methyl-1H-indole

Formula: C₉H₉N

Purity: 98%

Color and Shape: white to off-white crystalin (needle like) powder

Molecular weight: 131.17g/mol

Ref: 54-OR8470

5-Methylindole

CAS: 614-96-0

5-Methylindole is a molecule that has been found to be active against Staphylococcus aureus. This drug interferes with the synthesis of glycogen, which is an important energy storage molecule in animals. 5-Methylindole inhibits glycogen synthase kinase 3 (GSK-3) activity and thereby reduces the production of proinflammatory cytokines. This drug has also been shown to have cardiac effects, such as tachycardia and arrhythmias in mice. The optical properties of 5-methylindole are characterized by fluorescence and absorbance spectra, as well as its chemical reactions. 5-Methylindole is detectable at concentrations of 10 µg/mL and reacts with aminoglycosides by forming an adduct that can be detected using chromatographic methods.

Formula: C₉H₉N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 131.17 g/mol

Ref: 3D-FM32194

5-Methylindole

CAS: 614-96-0

Formula: C₉H₉N

Purity: 98%

Color and Shape: Solid

Molecular weight: 131.178

Ref: 10-F040072

5-Methylindole

Controlled Product

CAS: 614-96-0

Applications 5-Methylindole is used in the synthesis of novel protein kinase inhibitors.
References Guengerich, F. et al.: J. Med. Chem., 47, 3236 (2004);

Formula: C₉H₉N

Color and Shape: Neat

Molecular weight: 131.17

Ref: TR-M313505

5-Methylindole

CAS: 614-96-0

5-Methylindole is a chemical that has been used as a building block in the synthesis of many complex compounds. It has been found to be useful in research due to its versatility, and it can also be used as a reaction component in the synthesis of speciality chemicals. 5-Methylindole is an intermediate for other chemical compounds, and is an important solvent for some reactions. 5-Methylindole is also used as a reagent for the production of indole derivatives.

Formula: C₉H₉N

Purity: Min. 99 Area-%

Molecular weight: 131.18 g/mol

Ref: 3D-M-3914