CAS 61422-45-5: Carmofur
Description:Carmofur, with the CAS number 61422-45-5, is a synthetic compound primarily recognized for its application in cancer treatment, particularly in the management of colorectal cancer. It is classified as a fluorinated derivative of uracil, which is a pyrimidine nucleobase. Carmofur exhibits antitumor activity by inhibiting the enzyme thymidylate synthase, thereby interfering with DNA synthesis and cell proliferation. The compound is typically administered orally and is known for its relatively low toxicity compared to other chemotherapeutic agents. In addition to its anticancer properties, Carmofur has also been studied for its potential neuroprotective effects, particularly in neurodegenerative diseases. Its chemical structure includes a fluorine atom, which contributes to its biological activity. As with many pharmaceuticals, the use of Carmofur may be accompanied by side effects, and its efficacy can vary among individuals. Overall, Carmofur represents a significant compound in the field of oncology and continues to be the subject of research for its therapeutic potential.
Formula:C11H16FN3O3
InChI:InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
InChI key:InChIKey=AOCCBINRVIKJHY-UHFFFAOYSA-N
SMILES:O=C1NC(=O)N(C=C1F)C(=O)NCCCCCC
- Synonyms:
- 1(2H)-pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-
- 1-(Hexylcarbamoyl)-5-fluorouracil
- 1-(Hexylcarbamyl)-5-fluorouracil
- 1-(n-Hexylcarbamoyl)-5-fluorouracil
- 5-Fluoro-N-hexyl-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-carboxamide
- 5-Fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinecarboxamide
- 61422-45-5
- Mifurol
- Yamaful
- HCFU
- See more synonyms
