CAS 615-43-0

2-Iodoaniline

Description:

2-Iodoaniline, with the CAS number 615-43-0, is an organic compound that belongs to the class of anilines, which are aromatic amines. It features an amino group (-NH2) attached to a benzene ring that also has an iodine atom substituted at the second position. This compound is typically a pale yellow to brown solid and is known for its moderate solubility in organic solvents, while being less soluble in water due to the hydrophobic nature of the aromatic ring. 2-Iodoaniline is notable for its reactivity, particularly in electrophilic aromatic substitution reactions, where the iodine atom can influence the orientation and reactivity of the amino group. It is used in various applications, including as an intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals. Additionally, the presence of the iodine atom can impart unique properties, such as increased lipophilicity and potential biological activity. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested.

Formula: C₆H₆IN

InChI: InChI=1S/C6H6IN/c7-5-3-1-2-4-6(5)8/h1-4H,8H2

InChI key: InChIKey=UBPDKIDWEADHPP-UHFFFAOYSA-N

SMILES: IC1=C(N)C=CC=C1

Synonyms:

• 1-Amino-2-iodobenzene
• 2-Aminoiodobenzene
• 2-Aminophenyl iodide
• 2-Iodanilin
• 2-Iodoanilina
• 2-Iodoaniline
• 2-Iodobenzenamine
• 2-Iodophenylamine
• Aniline, 2-Iodo-
• Aniline, o-iodo-
• Nsc 34544
• o-Aminoiodobenzene
• o-Iodoaniline
• Benzenamine, 2-iodo-

2-Iodoaniline, 98+%

CAS: 615-43-0

2-Iodoaniline is used as an intermediate in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference

Formula: C₆H₆IN

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder or needles, White to cream to orange to brown

Molecular weight: 219.03

Ref: 02-A13059

2-Iodoaniline

CAS: 615-43-0

Formula: C₆H₆IN

Purity: 98.0%

Color and Shape: Solid, Crystalline Powder or Needles

Molecular weight: 219.025

Ref: 10-F001038

2-Iodoaniline

CAS: 615-43-0

Formula: C₆H₆IN

Purity: 98%

Color and Shape: Solid

Molecular weight: 219.0230

Ref: IN-DA003HGP

2-Iodoaniline

CAS: 615-43-0

Formula: C₆H₆IN

Purity: ≥ 98.0%

Color and Shape: Off-white to brown crystalline powder or crystals

Molecular weight: 219.03

Ref: 7W-GK1511

2-Iodobenzenamine

CAS: 615-43-0

2-Iodobenzenamine

Purity: ≥98%

Molecular weight: 219.02g/mol

Ref: 54-BUP19301

2-Iodoaniline

CAS: 615-43-0

Formula: C₆H₆IN

Purity: >98.0%(GC)(T)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 219.03

Ref: 3B-I0046

2-Iodoaniline

CAS: 615-43-0

2-Iodoaniline

Formula: C₆H₆IN

Purity: 98%

Color and Shape: off-white crystalline needles

Molecular weight: 219.02301g/mol

Ref: 54-OR1857

2-Iodobenzenamine

CAS: 615-43-0

2-Iodobenzenamine (NSC-34544) is an agent of biochemical.

Formula: C₆H₆IN

Purity: 99.95%

Color and Shape: Brown - Yellow Needles

Molecular weight: 219.02

Ref: TM-T20285

2-Iodoaniline

CAS: 615-43-0

2-Iodoaniline is a nucleophilic compound that reacts with electrophiles to form alkyl halides. It is used in the synthesis of β-aminoesters, which are used as γ-secretase inhibitors for the treatment of Alzheimer's disease. 2-Iodoaniline has been shown to be an effective inhibitor of protozoan parasites, such as Leishmania major and Trypanosoma cruzi, by blocking the conversion of pyruvate to oxaloacetate via enzymatic action. The chloride ion stabilizes the phenoxide anion intermediate and facilitates nucleophilic attack on the aromatic ring. 2-Iodoaniline has also been shown to be a competitive inhibitor of acylation reactions, due to its ability to bind covalently with acyl groups and inhibit their formation.

Formula: C₆H₆IN

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 219.02 g/mol

Ref: 3D-FI14200

2-Iodobenzenamine-d4

Controlled Product

CAS: 615-43-0

Formula: C₆D₄H₂IN

Color and Shape: Neat

Molecular weight: 223.048

Ref: TR-I693837

2-Iodoaniline

Controlled Product

CAS: 615-43-0

Applications 2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.
References Liu, J., et al.: Synthesis., 45, 943 (2013); Rambabu, D., et al.: Bioorg. Med. Chem. Lett., 23, 1351 (2013);

Formula: C₆H₆IN

Color and Shape: Yellow To Brown

Molecular weight: 219.02

Ref: TR-I693835