CAS 615-65-6

2-Chloro-4-methylaniline

Description:

2-Chloro-4-methylaniline, with the CAS number 615-65-6, is an aromatic amine characterized by the presence of both a chloro group and a methyl group attached to a benzene ring. Specifically, the chloro group is located at the second position and the methyl group at the fourth position relative to the amino group. This compound typically appears as a pale yellow to brown liquid or solid, depending on its purity and form. It is soluble in organic solvents but has limited solubility in water due to its hydrophobic aromatic structure. 2-Chloro-4-methylaniline is primarily used in the synthesis of dyes, pigments, and pharmaceuticals. It exhibits moderate toxicity and can pose health risks upon exposure, necessitating appropriate safety measures during handling. The compound's reactivity is influenced by the electron-donating methyl group and the electron-withdrawing chloro group, making it a useful intermediate in various chemical reactions, including nucleophilic substitutions and coupling reactions in organic synthesis.

Formula: C₇H₈ClN

InChI: InChI=1/C7H8ClN/c1-5-2-3-7(9)6(8)4-5/h2-4H,9H2,1H3

InChI key: InChIKey=XGYLSRFSXKAYCR-UHFFFAOYSA-N

SMILES: ClC1=C(N)C=CC(C)=C1

Synonyms:

• (2-Chloro-4-methylphenyl)amine
• 1-Amino-2-chloro-4-methylbenzene
• 2-Chloro-4-methylbenzenamine
• 2-Chloro-p-toluidine
• 2-Chloro-p-toluidine (NH2=1)
• 3-Chloro-4-aminotoluene
• 4-Amino-3-chlorotoluene
• 4-Methyl-2-chloroaniline
• Benzenamine, 2-chloro-4-methyl-
• NSC 60120
• p-Toluidine, 2-chloro-
• 2-Chloro-4-methylaniline
• 2-CHLORO-4-TOLUIDINE
• 2-chloro-4-methyl-benzenamin
• 2-Chloro-4-Methyl-Benzenamine
• 2-chlor-4-toluidine
• 2-Chloro-4-methylbenzamine
• 2-Chloro-4-methylaniline ,98%
• 2-CHLORO-PARA-TOLUIDINE
• ORTHO CHLORO PARA TOLUIDINE
• 2-Chlor-4-toluidin
• 2-chlor-4-toluidin(czech)
• 2-Chloro-p-toluidine, 4-Amino-3-chlorotoluene
• 2-CHLORO-4-METHYLANILINE/4-AMINO-3-CHLOROTOLUENE

2-Chloro-4-methylaniline

CAS: 615-65-6

Formula: C₇H₈ClN

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Red to Green clear liquid

Molecular weight: 141.60

Ref: 3B-A1437

2-Chloro-4-methylaniline, 98%

CAS: 615-65-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₈ClN

Purity: 98%

Color and Shape: Liquid, Clear pale yellow to yellow to brown to dark brown

Molecular weight: 141.60

Ref: 02-B22935

2-Chloro-4-methylaniline

CAS: 615-65-6

Formula: C₇H₈ClN

Purity: 97%

Color and Shape: Liquid

Molecular weight: 141.5981

Ref: IN-DA003GXF

2-Chloro-4-methylaniline

CAS: 615-65-6

Formula: C₇H₈ClN

Molecular weight: 141.60

Ref: 7W-GK5806

2-Chloro-4-methylaniline

Controlled Product

CAS: 615-65-6

Formula: C₇H₈ClN

Color and Shape: Neat

Molecular weight: 141.60

Ref: 04-C11429400

2-Chloro-4-methylaniline

CAS: 615-65-6

2-Chloro-4-methylaniline

Formula: C₇H₈ClN

Purity: ≥95%

Color and Shape: brown oil

Molecular weight: 141.60g/mol

Ref: 54-OR15009

2-Chloro-4-methylaniline

CAS: 615-65-6

Formula: C₇H₈ClN

Purity: 97%

Color and Shape: Liquid

Molecular weight: 141.6

Ref: 10-F036215

2-Chloro-4-methylaniline

CAS: 615-65-6

2-Chloro-4-methylaniline is a molecule that can be classified as an amine. It is a functional theory, which is a chemical ionization technique used to study the structure of molecules. 2-Chloro-4-methylaniline has been shown to have high metabolic profiles and to produce many metabolic products when it reacts with chlorine in the environment. This chemical has been studied extensively for its potential carcinogenic properties. It was found that 2-chloro-4-methylaniline causes DNA damage in human erythrocytes and induces mutations in calf thymus DNA, suggesting that this molecule may be carcinogenic. 2-Chloro-4-methylaniline also binds to hemoglobin, which may lead to the formation of methemoglobin that reduces oxygen transport in red blood cells. The matrix effect of this chemical on clinical pathology is not known.

Formula: C₇H₈ClN

Purity: Min. 95%

Molecular weight: 141.6 g/mol

Ref: 3D-FC05832

2-Chloro-4-Methylaniline

Controlled Product

CAS: 615-65-6

Applications 2-Chloro-4-methylaniline is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1.
References Chan, J., et al.: J. Med. Chem., 44, 1866 (2001);De La Rosa, M., et al.: Bioorg. Med. Chem. Lett., 16, 4444 (2006)

Formula: C₇H₈ClN

Color and Shape: Brown

Molecular weight: 141.60

Ref: TR-C368310