CAS 61521-74-2

(+)-Nortrachelogenin

Description:

(+)-Nortrachelogenin, with the CAS number 61521-74-2, is a naturally occurring alkaloid derived from various plant sources, particularly those in the family of Apocynaceae. This compound is characterized by its complex bicyclic structure, which contributes to its biological activity. It typically exhibits a chiral center, resulting in its designation as the (+) enantiomer, which is often associated with specific pharmacological effects. (+)-Nortrachelogenin has been studied for its potential therapeutic properties, including anti-inflammatory and analgesic effects, making it of interest in medicinal chemistry. Its solubility characteristics can vary, often being more soluble in organic solvents than in water, which is common for many alkaloids. The compound's stability and reactivity can be influenced by environmental factors such as pH and temperature. Overall, (+)-Nortrachelogenin represents a significant subject of study in natural product chemistry and pharmacology, with ongoing research aimed at elucidating its mechanisms of action and potential applications in medicine.

Formula: C₂₀H₂₂O₇

InChI: InChI=1S/C20H22O7/c1-25-17-8-12(3-5-15(17)21)7-14-11-27-19(23)20(14,24)10-13-4-6-16(22)18(9-13)26-2/h3-6,8-9,14,21-22,24H,7,10-11H2,1-2H3/t14-,20-/m1/s1

InChI key: InChIKey=ZITBJWXLODLDRH-JLTOFOAXSA-N

SMILES: C([C@H]1[C@@](CC2=CC(OC)=C(O)C=C2)(O)C(=O)OC1)C3=CC(OC)=C(O)C=C3

Synonyms:

• Wikstromol
• (3R,4R)-Dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
• 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-
• (+)-Nortrachelogenin
• 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R-cis)-

(+)-Nortrachelogenin

CAS: 61521-74-2

(+)-Nortrachelogenin

Purity: ≥98%

Molecular weight: 374.38g/mol

Ref: 54-BUP00807

(+)-Nortrachelogenin

CAS: 61521-74-2

Formula: C₂₀H₂₂O₇

Purity: 95%~99%

Molecular weight: 374.389

Ref: BP-SBP03665

(+)-Nortrachelogenin

CAS: 61521-74-2

(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.

Formula: C₂₀H₂₂O₇

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 374.38

Ref: TM-TN4673

(+)-Nortrachelogenin

CAS: 61521-74-2

(+)-Nortrachelogenin is a human macrophage and hl-60 cell activator. It is an acetate extract from the bark of the Nortrachelogenium tree that has been shown to have strong biological properties. The compound is composed of a hydroxyl group and a fatty acid, with the former being involved in the formation of a reactive oxygen species, which may cause oxidative stress on cells. (+)-Nortrachelogenin has been shown to be cytotoxic towards cervical cancer cells, while at the same time it has anti-tumor effects against prostate cancer cells. It also inhibits antibiotic-resistant strains such as E. coli K1 and S. pneumoniae, which makes it useful in treating bladder infections and other bacterial infections in general. The synergic effect of (+)-Nortrachelogenin with antibiotics was demonstrated by its ability to reduce bacterial growth by more than 50%.

Formula: C₂₀H₂₂O₇

Purity: Min. 95%

Molecular weight: 374.4 g/mol

Ref: 3D-LCA52174