CAS 61545-06-0

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6S)-

Description:

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6S)- is a complex organic compound characterized by its bicyclic structure, which includes a sulfur atom and an amine group. This compound features multiple functional groups, including carboxylic acids and an amide, contributing to its potential biological activity. The presence of a thienyl group suggests possible interactions with biological systems, making it of interest in medicinal chemistry. The sodium salt form indicates enhanced solubility in aqueous environments, which is beneficial for pharmacological applications. Its stereochemistry, denoted by the (2S,5R,6S) configuration, implies specific spatial arrangements that can influence its reactivity and interaction with biological targets. Overall, this compound's unique structural features and functional groups position it as a candidate for further research in drug development and therapeutic applications.

Formula: C₁₆H₁₈N₂O₇S₂

InChI: InChI=1/C16H18N2O7S2.2Na.2H/c1-15(2)9(12(22)23)18-13(24)16(25-3,14(18)27-15)17-10(19)8(11(20)21)7-4-5-26-6-7;;;;/h4-6,8-9,14H,1-3H3,(H,17,19)(H,20,21)(H,22,23);;;;/t8?,9-,14+,16?;;;;/m0..../s1/rC16H18N2O7S2.2HNa/c1-15(2)9(12(22)23)18-13(24)16(25-3,14(18)27-15)17-10(19)8(11(20)21)7-4-5-26-6-7;;/h4-6,8-9,14H,1-3H3,(H,17,19)(H,20,21)(H,22,23);2*1H/t8?,9-,14+,16?;;/m0../s1

InChI key: InChIKey=OSEDEUJPFFVLKH-CWBCWDDISA-N

SMILES: N(C(C(C(O)=O)C=1C=CSC1)=O)[C@@]2(OC)[C@@]3(N(C2=O)[C@@H](C(O)=O)C(C)(C)S3)[H].[Na]

Synonyms:

• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)amino)-6-methoxy-3,3-dimethyl-7-oxo-, disodium salt, (2S,5R,6S)-
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)amino)-6-methoxy-3,3-dimethyl-7-oxo-, disodium salt, (2S-(2alpha,5alpha,6alpha))-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-6-methoxy-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2α,5α,6α)]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6S)-
• Antibiotic BRL 17421
• Brl 17421
• Disodium (2S-(2alpha,5alpha,6alpha))-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
• Temocillin disodium salt
• (2S,5R,6S)-6-[[2-Carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
• Temocillindisodiumsalt
• BRL 17421 disodium

Temocillin disodium

CAS: 61545-06-0

Temocillin disodium

Purity: ≥90%

Molecular weight: 458.42g/mol

Ref: 54-BUP21672

Temocillin disodium

CAS: 61545-06-0

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity and can be used to study urinary tract infections.

Formula: C₁₆H₁₆N₂Na₂O₇S₂

Purity: 92.30%

Color and Shape: Solid

Molecular weight: 458.42

Ref: TM-T40699

Temocillin Disodium

CAS: 61545-06-0

Formula: C₁₆H₁₈N₂O₇S₂·2Na

Molecular weight: 414.45 2 22.99

Ref: 4Z-T-279001

Temocillin disodium

CAS: 61545-06-0

Temocillin disodium is a beta-lactamase-resistant penicillin antibiotic with action on bacterial cell wall synthesis and is used for treating infections caused by multidrug-resistant gram-negative bacteria.

Formula: C₁₆H₁₆N₂Na₂O₇S₂

Purity: Min. 81 Area-%

Color and Shape: White Powder

Molecular weight: 458.42 g/mol

Ref: 3D-FT32659

Temocillin Disodium

Controlled Product

CAS: 61545-06-0

Applications Temocillin Disodium is the salt of Temocillin, which is a β-lactam stable against most β-lactamases is used as an alternative to carbapenems.
References Balakrishnan, I. et al.: J. Antimicrob. Chemother., 66, 2628 (2011);

Formula: C₁₆H₁₆N₂O₇S₂·2Na

Color and Shape: Neat

Molecular weight: 458.417

Ref: TR-T017320