CAS 61556-44-3

2'-O-methylguanosine 5'-(tetrahydrogen triphosphate)

Description:

2'-O-methylguanosine 5'-(tetrahydrogen triphosphate), commonly referred to as 2'-O-methyl-GTP, is a modified nucleotide that plays a significant role in various biochemical processes, particularly in RNA synthesis and modification. This compound features a guanosine base with a methyl group at the 2' position of the ribose sugar, which enhances its stability and influences its interactions with RNA polymerases and other proteins. The presence of the triphosphate group is crucial for its function, as it provides the necessary energy for RNA synthesis and serves as a substrate for various enzymatic reactions. 2'-O-methyl-GTP is often used in research and therapeutic applications, particularly in the development of RNA-based drugs and in the study of RNA structure and function. Its unique properties, such as increased resistance to degradation by nucleases, make it a valuable tool in molecular biology. Overall, 2'-O-methylguanosine 5'-(tetrahydrogen triphosphate) is an important compound in the field of biochemistry and molecular biology.

Formula: C₁₁H₁₈N₅O₁₄P₃

InChI: InChI=1/C11H18N5O14P3/c1-26-7-6(17)4(2-27-32(22,23)30-33(24,25)29-31(19,20)21)28-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-/m1/s1

SMILES: CO[C@@H]1[C@@H]([C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O[C@H]1n1cnc2c1[nH]c(=N)nc2O)O

2'-O-Methylguanosine-5'-triphosphate sodium salt - 100mM aqueous solution

CAS: 61556-44-3

2'-O-Methylguanosine-5'-triphosphate sodium salt is a nucleotide that is synthesized by the phosphorylation of guanosine at the 5' position. It has been shown to have significant activation of cardiac protein synthesis and translation. This nucleotide has also been shown to stabilize RNA in vitro, which may be due to its ability to activate adenylate cyclase activity. 2'-O-Methylguanosine-5'-triphosphate sodium salt is a potent inhibitor of hepatitis B virus replication, but does not inhibit the replication of other viruses.

Formula: C₁₀H₁₈N₃O₁₄P₃·Na

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 520.17 g/mol

Ref: 3D-NM157274

2'-O-Methylguanosine 5'-triphosphate lithium salt - 100mM aqueous solution

CAS: 61556-44-3

2'-O-Methylguanosine 5'-triphosphate lithium salt is a synthetic nucleotide

Formula: C₁₁H₁₈N₅O₁₄P₃·xLi

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 537.21 g/mol

Ref: 3D-NM58211