CAS 6160-65-2

Thiocarbonyldiimidazole

Description:

Thiocarbonyldiimidazole (TCDI) is a chemical compound characterized by its unique structure, which includes two imidazole rings and a thiocarbonyl functional group. It is typically used as a coupling agent in organic synthesis, particularly in the formation of thioesters and in peptide synthesis. TCDI is known for its ability to activate carboxylic acids, facilitating the formation of amides and esters. The compound is generally stable under standard conditions but should be handled with care due to its reactivity and potential to release toxic byproducts upon decomposition. TCDI is soluble in organic solvents, making it suitable for various applications in organic chemistry. Its reactivity is attributed to the electrophilic nature of the thiocarbonyl group, which can interact with nucleophiles. Overall, TCDI is a valuable reagent in synthetic organic chemistry, particularly in the development of pharmaceuticals and other complex organic molecules. Proper safety measures should be observed when handling this compound due to its potential hazards.

Formula: C₇H₆N₄S

InChI: InChI=1S/C7H6N4S/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H

InChI key: InChIKey=RAFNCPHFRHZCPS-UHFFFAOYSA-N

SMILES: C(=S)(N1C=CN=C1)N2C=CN=C2

Synonyms:

• 1,1-Thiocarbonylbis(Imidazole)
• 1,1′-(Thiocarbonyl)bis[imidazole]
• 1,1′-(Thiocarbonyl)diimidazole
• 1-(1H-Imidazol-1-ylcarbothioyl)-1H-imidazole
• 1-(1H-Imidazole-1-carbothioyl)-1H-imidazole
• 1H-Imidazole, 1,1′-carbonothioylbis-
• Di(1H-imidzazol-1-yl)methanethione
• Diimidazol-1-ylmethanethione
• Im₂CS
• Imidazole, 1,1′-(thiocarbonyl)di-
• Methanethione, di-1H-imidazol-1-yl-
• N,N'-Thiocarbonyldiimidazole
• NSC 141692
• Tcdi
• Thiocarbonylbisimidazole
• Thiocarbonyldiimidazole

1,1'-Thiocarbonyldiimidazole

CAS: 6160-65-2

Formula: C₇H₆N₄S

Purity: >95.0%(GC)(T)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 178.21

Ref: 3B-C1376

1,1'-Thiocarbonyldiimidazole, tech 90%

CAS: 6160-65-2

1,1'-Thiocarbonyldiimidazole is used as a reagent for the deoxygenation of alcohols with tributyltin hydride and diols with lithium aluminum hydride. It is also used to deoxygenate carboxylic monosaccharide analogues. Further, it is a useful reagent involved in biochemical synthesis. In addition to

Formula: C₇H₆N₄S

Purity: 90%

Color and Shape: Yellow, Powder

Molecular weight: 178.21

Ref: 02-B22008

1,1-Thiocarbonyldiimidazole

CAS: 6160-65-2

Formula: C₇H₆N₄S

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 178.21

Ref: 10-F035595

1,1'-Thiocarbonyldiimidazole

CAS: 6160-65-2

Formula: C₇H₆N₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 178.2143

Ref: IN-DA0032JV

1,1'-Thiocarbonyldi(1H-imidazole)

CAS: 6160-65-2

1,1'-Thiocarbonyldi(1H-imidazole)

Formula: C₇H₆N₄S

Purity: 94%

Color and Shape: yellow solid

Molecular weight: 178.21g/mol

Ref: 54-OR5389

1,1''-Thiocarbonyldiimidazole

CAS: 6160-65-2

Formula: C₇H₆N₄S

Molecular weight: 178.22

Ref: 7W-GK6138

N,N'-Thiocarbonyldiimidazole

CAS: 6160-65-2

N,N'-Thiocarbonyldiimidazole is a potent inhibitor of the enzyme acetylcholinesterase. It is used in research as an inhibitor molecule for receptor activity and to study the mechanism of action of other drugs. N,N'-Thiocarbonyldiimidazole inhibits the production of ester hydrochloride by rat liver microsomes and muscle cell proliferation. In addition, this compound has been shown to be a protonophore that can transport protons across membranes without energy input. This can be done through Langmuir adsorption isotherm and electrochemical impedance spectroscopy.

Formula: C₇H₆N₄S

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 178.22 g/mol

Ref: 3D-FT53775

1,1’-Thiocarbonyldiimidazole

Controlled Product

CAS: 6160-65-2

Applications 1,1’-Thiocarbonyldiimidazole can be used to deoxygenate carboxylic monosaccharide analogues.
References Loke, I., et al.: Tetrahedron, 68, 697 (2012),

Formula: C₇H₆N₄S

Color and Shape: Neat

Molecular weight: 178.214

Ref: TR-T344410