CAS 616201-80-0

Lorcaserin A

Description:

Lorcaserin A, with the CAS number 616201-80-0, is a selective serotonin 2C receptor agonist that was primarily developed for the treatment of obesity. It functions by promoting a feeling of satiety, thereby aiding in weight loss. The compound is characterized by its ability to modulate appetite through its action on the central nervous system. Lorcaserin A has a relatively low affinity for other serotonin receptor subtypes, which contributes to its favorable side effect profile compared to other weight-loss medications. Its pharmacokinetics include oral bioavailability, and it is metabolized primarily in the liver. The substance has undergone various clinical trials to assess its efficacy and safety, demonstrating significant weight loss in participants compared to placebo. However, it is important to note that Lorcaserin A was withdrawn from the market due to concerns about potential cardiovascular risks. Overall, while it showed promise as an anti-obesity agent, its clinical use has been limited by safety considerations.

Formula: C₁₁H₁₄ClN

Synonyms:

• 8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
• LorcaserinA

8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Controlled Product

CAS: 616201-80-0

8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine is an antipsychotic drug that is a member of the class of drugs known as serotonin receptor antagonists. It is a synthetic process that has been used to produce antidepressant and antipsychotic drugs. This drug was first synthesized in 1966 by chemists at Smith Kline & French Laboratories as part of a program to develop novel antidepressants. 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine is one of the few antipsychotics that does not cause extrapyramidal side effects such as tardive dyskinesia. The enantiomers are active with the (S) form being more potent than the (R) form.

Formula: C₁₁H₁₄ClN

Purity: Min. 95%

Molecular weight: 195.69 g/mol

Ref: 3D-FC148171