CAS 61661-05-0
:(+)-Dobutamine
Description:
(+)-Dobutamine is a synthetic catecholamine and a potent inotropic agent primarily used in clinical settings to treat heart failure and cardiogenic shock. It is characterized by its ability to stimulate beta-1 adrenergic receptors, leading to increased cardiac contractility and heart rate, while also exhibiting some beta-2 adrenergic activity that can cause vasodilation. The compound is typically administered intravenously due to its rapid onset of action and short half-life. Chemically, (+)-Dobutamine is a chiral molecule, with its specific stereochemistry contributing to its pharmacological effects. It is soluble in water, which facilitates its use in medical formulations. The substance is generally well-tolerated, though it may cause side effects such as increased heart rate, hypertension, and arrhythmias in some patients. As a result, careful monitoring is essential during its administration. Overall, (+)-Dobutamine plays a critical role in acute cardiac care, providing essential support for patients with compromised heart function.
Formula:C18H23NO3
Synonyms:- 1,2-Benzenediol, 4-[2-[[(1R)-3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-
- 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, (R)-
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