CAS 61671-80-5
:Uridine,5-fluoro-2'-O-methyl-
Description:
Uridine, 5-fluoro-2'-O-methyl- (CAS 61671-80-5) is a modified nucleoside that features a uridine backbone with specific substitutions that enhance its biochemical properties. The presence of a fluorine atom at the 5-position and a methoxy group at the 2'-position distinguishes it from standard uridine. This modification can influence its stability, solubility, and interaction with nucleic acid targets, making it of interest in various biochemical and pharmaceutical applications. Typically, such modifications can enhance the compound's resistance to enzymatic degradation, potentially increasing its efficacy in therapeutic contexts, particularly in antiviral and anticancer research. The compound is generally characterized by its molecular formula, which reflects the presence of carbon, hydrogen, nitrogen, oxygen, and fluorine atoms. Its structural modifications may also affect its binding affinity to RNA and DNA, making it a valuable tool in molecular biology studies. Overall, Uridine, 5-fluoro-2'-O-methyl- represents a significant area of interest in the development of nucleoside analogs for therapeutic use.
Formula:C10H13FN2O6
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Found 2 products.
5-Fluoro-2'-O-methyluridine
CAS:<p>5-Fluoro-2'-O-methyluridine is a nucleotide that can be used in the treatment of colorectal adenocarcinoma and other types of cancer. It inhibits the synthesis of DNA by blocking the activity of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. 5-Fluoro-2'-O-methyluridine has been shown to decrease the growth of human glioblastoma cells in cell culture and animal models. The effect is dose dependent and occurs through inhibition of RNA synthesis and protein synthesis, leading to cell death.</p>Formula:C10H13FN2O6Purity:Min. 95%Molecular weight:276.22 g/mol
