CAS 6170-42-9

Chloropyramine hydrochloride

Description:

Chloropyramine hydrochloride is an antihistamine belonging to the phenothiazine class, primarily used for its antiallergic properties. It is characterized by its ability to block H1 histamine receptors, thereby alleviating symptoms associated with allergic reactions, such as itching, sneezing, and runny nose. The compound appears as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly bitter taste. Its chemical structure includes a pyrimidine ring, contributing to its pharmacological activity. Chloropyramine hydrochloride is often utilized in the treatment of allergic conditions, including hay fever and urticaria, and may also have sedative effects due to its central nervous system activity. As with many antihistamines, it may cause side effects such as drowsiness, dry mouth, and dizziness. Proper dosage and administration are crucial to minimize adverse effects and ensure therapeutic efficacy. It is important to consult healthcare professionals for appropriate use and to be aware of potential interactions with other medications.

Formula: C₁₆H₂₀ClN₃·ClH

InChI: InChI=1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H

InChI key: InChIKey=VEYWWAGBHABATA-UHFFFAOYSA-N

SMILES: N(CC1=CC=C(Cl)C=C1)(CCN(C)C)C2=CC=CC=N2.Cl

Synonyms:

• 1,2-Ethanediamine, N-((4-chlorophenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-, monohydrochloride (9CI)
• 1,2-Ethanediamine, N-[(4-chlorophenyl)methyl]-N′,N′-dimethyl-N-2-pyridinyl-, monohydrochloride
• 1,2-Ethanediamine, N¹-[(4-chlorophenyl)methyl]-N²,N²-dimethyl-N¹-2-pyridinyl-, hydrochloride (1:1)
• 2-[(4-chlorobenzyl)(pyridin-2-yl)amino]-N,N-dimethylethanaminium chloride
• Alergosan
• Allergan S hydrochloride
• Cfak-C 4
• Chloropyramine HCl
• Chloropyribenzamine hydrochloride
• Chlorpiramin hydrochloride
• Chlorpyramine hydrochloride
• G 12144
• Halopyramine hydrochloride
• N-(β-Dimethylaminoethyl)-N-(p-chlorobenzyl)-α-aminopyridine hydrochloride
• Nilfan
• Nsc 409949
• Pyridine, 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-, monohydrochloride (8CI)
• Pyridine, 2-[(p-chlorobenzyl)[2-(dimethylamino)ethyl]amino]-, monohydrochloride
• Sinopen
• Sinopen hydrochloride
• Suprastin
• Suprastin hydrochloride
• Unii-Fwa92Z14Nn
• Chloropyramine hydrochloride

Chloropyramine hydrochloride

CAS: 6170-42-9

Competitive reversible H-1 receptor antagonist

Formula: C₁₆H₂₀ClN₃•HCl

Molecular weight: 326.26

Ref: 02-J60350

Chloropyramine Hydrochloride

CAS: 6170-42-9

Color and Shape: White Solid

Ref: 61-FOR1894.00

N1-(4-Chlorobenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride

CAS: 6170-42-9

Formula: C₁₆H₂₁Cl₂N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 326.2640

Ref: IN-DA003OUK

Chloropyramine hydrochloride

CAS: 6170-42-9

Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.

Formula: C₁₆H₂₀ClN₃·HCl

Purity: 99.45% - 99.8%

Color and Shape: Solid

Molecular weight: 326.26

Ref: TM-T0263

Chloropyramine hydrochloride

CAS: 6170-42-9

Formula: C₁₆H₂₀ClN₃·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 326.26

Ref: 7W-GX9288

Chloropyramine hydrochloride

CAS: 6170-42-9

Chloropyramine hydrochloride

Purity: ≥98%

Molecular weight: 326.26g/mol

Ref: 54-BUP16269

N1-(4-Chlorobenzyl)-N2,N2-Dimethyl-N1-(Pyridin-2-Yl)Ethane-1,2-Diamine Hydrochloride

CAS: 6170-42-9

N1-(4-Chlorobenzyl)-N2,N2-Dimethyl-N1-(Pyridin-2-Yl)Ethane-1,2-Diamine Hydrochloride

Purity: 98%

Molecular weight: 326.26g/mol

Ref: 54-OR1026294

Chloropyramine Hydrochloride

CAS: 6170-42-9

Formula: C₁₆H₂₀ClN₃·ClH

Color and Shape: White Solid

Molecular weight: 326.26

Ref: 86-MM1894.00

Chloropyramine Hydrochloride

CAS: 6170-42-9

Applications Chloropyramine hydrochloride is a neurotransmitter related agent for research of drug analysis. Also, it is designed to disrupt the focal adhesion kinase (FAK) and vascular endothelial growth factor receptor-3 (VEGFR-3) interaction in neuroblastoma.
References Stewart, J. E., et al.: Mol. Carcinog., 54, 9-23 (2015)

Formula: C₁₆H₂₀ClN₃·ClH

Color and Shape: Neat

Molecular weight: 326.26

Ref: TR-C381268

Chloropyramine HCl

CAS: 6170-42-9

Chloropyramine is a drug that has been used to treat autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. It is an antihistamine drug that acts by blocking the histamine receptor. Chloropyramine has been shown to have an effect on diastolic pressure in animal models. The model system used was human serum with locomotor activity as the endpoint. The sample preparation involved calcium pantothenate, which is a precursor of coenzymes A and C. The pharmacological agent chloropyramine binds to the agonist binding site, which is located at the end of the cell membrane and regulates ion channels, including those for calcium ions. Tricyclic antidepressant drugs are known to bind to this same binding site, inhibiting the action of both histamine and chloropyramine. Histamine causes increased blood flow due to vasodilation by stimulating H1 receptors in smooth muscles cells. Histamine

Formula: C₁₆H₂₀ClN₃·HCl

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 326.26 g/mol

Ref: 3D-FC149051

N1-(4-Chlorobenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride

CAS: 6170-42-9

Formula: C₁₆H₂₁Cl₂N₃

Purity: ≥98%

Molecular weight: 326.27

Ref: 10-F324024

Chloropyramine Hydrochloride

CAS: 6170-42-9

Formula: C₁₆H₂₀ClN₃HCl

Molecular weight: 289.8 : 36.5

Ref: ST-EA-CP-C341008