CAS 61714-27-0
:W-7 Hydrochloride
Description:
W-7 Hydrochloride, with the CAS number 61714-27-0, is a synthetic compound known primarily as a calmodulin inhibitor. It is a derivative of the peptide W-7, which is designed to interfere with the calcium-binding protein calmodulin, thereby modulating various calcium-dependent cellular processes. This compound is typically characterized by its ability to inhibit calmodulin-mediated signal transduction pathways, making it a valuable tool in biochemical research, particularly in studies related to muscle contraction, neurotransmitter release, and cell proliferation. W-7 Hydrochloride is usually presented as a white to off-white crystalline powder and is soluble in water and organic solvents, which facilitates its use in various experimental setups. Safety data sheets indicate that, like many chemical substances, it should be handled with care, as it may pose health risks if ingested or inhaled. Overall, W-7 Hydrochloride serves as an important reagent in pharmacological and biochemical studies, contributing to the understanding of calcium signaling in cells.
Formula:C16H21ClN2O2S·ClH
InChI:InChI=1S/C16H21ClN2O2S.ClH/c17-15-9-5-8-14-13(15)7-6-10-16(14)22(20,21)19-12-4-2-1-3-11-18;/h5-10,19H,1-4,11-12,18H2;1H
InChI key:InChIKey=OMMOSRLIFSCDBL-UHFFFAOYSA-N
SMILES:S(NCCCCCCN)(=O)(=O)C=1C2=C(C(Cl)=CC=C2)C=CC1.Cl
Synonyms:- W-7 Hydrochloride
- 1-Naphthalenesulfonamide, N-(6-aminohexyl)-5-chloro-, monohydrochloride
- NSC 683545
- W 7
- 1-Naphthalenesulfonamide, N-(6-aminohexyl)-5-chloro-, hydrochloride (1:1)
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Found 7 products.
N-(6-Aminohexyl)-5-chloronaphthalene-1-sulfonamide hydrochloride
CAS:Formula:C16H22Cl2N2O2SPurity:98%Color and Shape:SolidMolecular weight:377.3291N-(6-Aminohexyl)-5-chloronaphthalene-1-sulphonamide hydrochloride
CAS:<p>N-(6-Aminohexyl)-5-chloronaphthalene-1-sulphonamide hydrochloride</p>Formula:C16H21ClN2O2S·ClHPurity:≥95%Molecular weight:377.33g/molW-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Formula:C16H22Cl2N2O2SPurity:99.63%Color and Shape:White Crystalline SolidMolecular weight:377.32N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride
CAS:Controlled Product<p>Applications W7 is a vascular relaxing agent which affects vascular smooth muscle actomyosin. W7, an inhibitor of actomyosin superprecipitation, produces relaxation of isolated rabbit arterial strips and antagonizes the contraction of the strips induced by various contractile agonists. W7 is also a calmodulin antagonist that binds to calmodulin and inhibits Ca2+/calmodulin-regulated enzyme activities.<br>References Hidaka, H., et al.: Proc. Nat. Acad. Sci. USA, 78, 4354 (1981)<br></p>Formula:C16H21ClN2O2S·ClHColor and Shape:NeatMolecular weight:377.33N-(6-AMINOHEXYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL
CAS:Purity:≥98%(HPLC)Molecular weight:377.3200073





