CAS 61845-39-4

thymidylyl(3'5')-2'-deoxyadenosine*ammonium

Description:

Thymidylyl(3'5')-2'-deoxyadenosine ammonium, also known by its CAS number 61845-39-4, is a nucleotide analog that plays a significant role in biochemical research, particularly in studies involving nucleic acids. This compound consists of a thymidine moiety linked to a deoxyadenosine unit through a phosphodiester bond, specifically in a 3',5'-linkage configuration. The presence of the ammonium group suggests that it may exist in a protonated form, which can influence its solubility and interaction with biological macromolecules. This substance is typically used in the synthesis of oligonucleotides and can serve as a substrate for various enzymatic reactions, including those catalyzed by polymerases. Its structural characteristics allow it to participate in base pairing and hybridization processes, making it valuable in molecular biology applications such as PCR and DNA sequencing. Additionally, the compound's stability and reactivity can be influenced by environmental factors such as pH and ionic strength, which are critical for its functionality in biological systems.

Formula: C₂₀H₂₉N₈O₁₀P

InChI: InChI=1/C20H26N7O10P.H3N/c1-9-4-26(20(31)25-19(9)30)15-3-11(12(5-28)35-15)37-38(32,33)34-6-13-10(29)2-14(36-13)27-8-24-16-17(21)22-7-23-18(16)27;/h4,7-8,10-15,28-29H,2-3,5-6H2,1H3,(H,32,33)(H2,21,22,23)(H,25,30,31);1H3

SMILES: Cc1cn(C2CC(C(CO)O2)OP(=O)(O)OCC2C(CC(n3cnc4c(N)ncnc34)O2)O)c(=O)nc1O.N

Thymidylyl-(3''-5'')-2''-deoxyadenosine ammonium salt

CAS: 61845-39-4

Formula: C₂₀H₂₄N₇O₁₀PNH₃

Molecular weight: 570.45

Ref: 7W-GN3850

Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt

CAS: 61845-39-4

Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.

Formula: C₂₀H₂₆N₇O₁₀P·NH₃

Purity: Min. 95%

Molecular weight: 572.47 g/mol

Ref: 3D-NT08058