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CAS 61848-66-6

:

Dichloro[(1R,2R)-1,2-cyclohexanediamine]platinum

Description:
Dichloro[(1R,2R)-1,2-cyclohexanediamine]platinum, with the CAS number 61848-66-6, is a coordination compound of platinum characterized by its square planar geometry, typical of platinum(II) complexes. This compound features a platinum center coordinated to two chloride ions and a bidentate ligand, specifically (1R,2R)-1,2-cyclohexanediamine, which provides a chelating effect due to its two amine groups. The chirality of the cyclohexanediamine ligand contributes to the compound's stereochemistry, influencing its biological activity and interaction with biomolecules. Dichloro[(1R,2R)-1,2-cyclohexanediamine]platinum is of interest in medicinal chemistry, particularly in the development of anticancer agents, as it may exhibit cytotoxic properties similar to other platinum-based drugs like cisplatin. Its solubility and stability in various solvents can vary, affecting its reactivity and potential applications. Overall, this compound exemplifies the significance of metal coordination in drug design and the importance of ligand choice in determining the properties of metal complexes.
Formula:C6H12Cl2N2Pt
InChI:InChI=1S/C6H14N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-6H,1-4,7-8H2;2*1H;/q;;;+2/p-2/t5-,6-;;;/m1.../s1
InChI key:InChIKey=PNNCIXRVXCLADM-SKSSAGQDSA-L
SMILES:[Cl-][Pt+2]1([Cl-])[NH2][C@]2([C@]([NH2]1)(CCCC2)[H])[H]
Synonyms:
  • Platinum, dichloro[(1R,2R)-1,2-cyclohexanediamine-κN1,κN2]-, (SP-4-2)-
  • 1,2-Cyclohexanediamine, platinum complex, (1R-trans)-
  • Platinum, dichloro(1,2-cyclohexanediamine-N,N′)-, [SP-4-2-(1R-trans)]-
  • Platinum, dichloro[(1R,2R)-1,2-cyclohexanediamine-κN,κN′]-, (SP-4-2)-
  • (SP-4-2)-Dichloro[(1R,2R)-1,2-cyclohexanediamine-κN1,κN2]platinum
  • Nsc265460
  • Oxaliplatin System Suitability (25 mg)
  • [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N') dichlorideplatinum(II)
  • Oxaliplatin System Suitability ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N'') dichloridoplatinu (1481306)
  • Cis-Dichloro-(1R)-trans-1,2-cyclohexanediaMine platinuM(Ⅱ)
  • See more synonyms
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