CAS 61849-14-7

Epoprostenol sodium

Description:

Epoprostenol sodium, with the CAS number 61849-14-7, is a synthetic analog of prostacyclin, a naturally occurring prostaglandin. It is primarily used as a potent vasodilator and platelet aggregation inhibitor, making it valuable in the treatment of pulmonary arterial hypertension and other cardiovascular conditions. Epoprostenol sodium is characterized by its ability to relax vascular smooth muscle, leading to increased blood flow and reduced blood pressure in the pulmonary and systemic circulation. The substance is typically administered intravenously due to its short half-life and instability in solution. Its chemical structure features a bicyclic ring system with multiple functional groups, contributing to its biological activity. Epoprostenol sodium is also known for its rapid metabolism, primarily by the lungs, which necessitates continuous infusion for therapeutic efficacy. As with any medication, it may have side effects, including hypotension, flushing, and headache, and requires careful monitoring during administration.

Formula: C₂₀H₃₁NaO₅

InChI: InChI=1/C20H32O5.Na/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22;/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24);/q;+1/p-1/b11-10+,15-8u;/t14-,16+,17+,18+,19-;/m0./s1

InChI key: InChIKey=WHVPOEPABJZBBY-XQYLJSSYSA-N

SMILES: C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@]2([C@@](O/C(=C\CCCC(O)=O)/C2)(C[C@H]1O)[H])[H].[Na]

Synonyms:

• Cyclo-Prostin
• Flolan
• PGI₂ sodium
• PGI₂ sodium salt
• Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, monosodium salt, (5Z,9α,11α,13E,15S)-
• Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, sodium salt (1:1), (5Z,9α,11α,13E,15S)-
• Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, sodium salt, (5Z,9alpha,11alpha,13E,15S)-
• Prostacyclin Sodium Salt
• Prostacyclin sodium
• Sodium (5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dien-1-oate
• Sodium (Z)-(3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-((E)-(3S)-3-hydroxy-1-octenyl)-2H-cyclopenta(b)furan-delta(sup 2,delta)-valerate
• Sodium PGI₂
• Sodium prostacyclin
• U 53,217A
• Unii-4K04Iq1Of4
• Veletri
• sodium (5Z,9alpha,11alpha,13E,15S)-11,15-dihydroxy-6,9-epoxyprosta-5,13-dien-1-oate
• sodium (9alpha,11alpha,13E,15S)-11,15-dihydroxy-6,9-epoxyprosta-5,13-dien-1-oate
• Sodium PGI2
• PGI2 sodium salt
• PGI2
• EPOPROSTENOL SODIUM
• PROSTAGLANDIN I2 NA
• 6,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT
• EPOPROSTENOL SODIUM SALT
• Prostaglandin 12
• (5-Z)-9-DEOXY-6,9ALPHA-EPOXY-PGF1ALPHA, SODIUM SALT
• PGI2-NA
• PROSTAGLANDIN I2
• PG12-NA
• PROSTACYCLINE SODIUM SALT
• (5z,9α,11α,13e,15s)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
• EPOPROSTENOL
• PROSTAGLANDINS I2 SODIUM SALT
• PROSTAGLANDIN I2 SODIUM
• PROSTAGLANDIN I2 SODIUM SALT

Epoprostenol Sodium

CAS: 61849-14-7

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

Formula: C₂₀H₃₁NaO₅

Color and Shape: White Off-White Powder

Molecular weight: 374.20692

Ref: 45-1237600

Prostaglandin I2 sodium salt

CAS: 61849-14-7

Formula: C₂₀H₃₁NaO₅

Molecular weight: 374.45

Ref: 7W-GL0994

Epoprostenol sodium

CAS: 61849-14-7

Epoprostenol sodium (Prostaglandin I2 sodium salt) is a vasodilator and a synthetic prostacyclin that can be used to study pulmonary hypertension.

Formula: C₂₀H₃₁NaO₅

Purity: 98%

Color and Shape: White Crystalline Powder

Molecular weight: 374.45

Ref: TM-T15238

Prostacyclin Sodium Salt

CAS: 61849-14-7

Formula: C₂₀H₃₁O₅Na

Molecular weight: 351.46 22.99

Ref: 4Z-P-254004

Prostacyclin sodium

CAS: 61849-14-7

Prostacyclin is a non-steroidal anti-inflammatory drug that inhibits the production of prostaglandin, which is an inflammatory agent. Prostacyclin has been shown to be effective in the treatment of primary pulmonary hypertension and pulmonary hypertension. The mechanism of action of prostacyclin is not fully understood, but it appears to inhibit neuronal death and reduce the severity of pulmonary hypertension. Prostacyclin also has inhibitory properties on prostaglandins I2 (PGI2) receptors.

Formula: C₂₀H₃₂NaO₅

Purity: Min. 95%

Molecular weight: 375.45 g/mol

Ref: 3D-FP27241