CymitQuimica logo

CAS 61869-08-7

:

(-)-Paroxetine

Description:
(-)-Paroxetine is a selective serotonin reuptake inhibitor (SSRI) primarily used in the treatment of major depressive disorder, anxiety disorders, and obsessive-compulsive disorder. It is characterized by its chiral nature, existing as a single enantiomer, which contributes to its pharmacological activity. The molecular formula of (-)-Paroxetine is C19H20FNO3, and it features a piperidine ring, a phenyl group, and a fluorine atom, which are integral to its structure and function. The compound exhibits a moderate to high lipophilicity, allowing it to cross the blood-brain barrier effectively. Its mechanism of action involves the inhibition of serotonin reuptake in the synaptic cleft, leading to increased serotonin levels in the brain, which is associated with mood regulation. (-)-Paroxetine is typically administered in oral form and has a half-life that allows for once-daily dosing. However, it may cause side effects, including gastrointestinal disturbances, sexual dysfunction, and withdrawal symptoms upon discontinuation, necessitating careful management during treatment.
Formula:C19H20FNO3
InChI:InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1
InChI key:InChIKey=AHOUBRCZNHFOSL-YOEHRIQHSA-N
SMILES:C(OC=1C=C2C(=CC1)OCO2)[C@H]3[C@@H](CCNC3)C4=CC=C(F)C=C4
Synonyms:
  • FG 7051
  • Paroxetine
  • Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, (3S-trans)-
  • (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
  • (3S,4R)-1-Methyl-3-[(3,4-(methylene-dioxy)phenoxy)METHYL]-4-(4-fluorophenyl) piperidine
  • Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, (3S,4R)-
  • (4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
  • 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
  • PAROXETIENE BASE
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.