CAS 61881-19-4

(1Z)-2,2,2-trifluoro-N-phenyl-acetimidoyl chloride

Description:

(1Z)-2,2,2-Trifluoro-N-phenyl-acetimidoyl chloride, with the CAS number 61881-19-4, is an organic compound characterized by its unique functional groups and fluorinated structure. It features a trifluoromethyl group, which imparts significant electronegativity and influences its reactivity and polarity. The presence of the imidoyl chloride functional group suggests that it can participate in nucleophilic substitution reactions, making it a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. The phenyl group contributes to the compound's aromatic character, enhancing its stability and influencing its interaction with other molecules. This compound is typically handled with caution due to its reactive nature, particularly the chloride moiety, which can release hydrochloric acid upon hydrolysis. Additionally, the trifluoromethyl group can enhance lipophilicity, affecting the compound's solubility and biological activity. Overall, (1Z)-2,2,2-trifluoro-N-phenyl-acetimidoyl chloride is a versatile reagent in synthetic organic chemistry, with applications in various chemical transformations.

Formula: C₈H₅ClF₃N

InChI: InChI=1/C8H5ClF3N/c9-7(8(10,11)12)13-6-4-2-1-3-5-6/h1-5H

Synonyms:

• 2,2,2-Trifluoro-N-phenylethanimidoyl chloride
• ethanimidoyl chloride, 2,2,2-trifluoro-N-phenyl-
• 2,2,2-Trifluoro-N-phenylacetimidoyl Chloride
• N-Phenyltrifluoroacetimidoyl chloride
• -phenylacetimidoyl Chloride
• N
• 2,2,2-Trifluoro-

2,2,2-Trifluoro-N-phenylacetimidoyl Chloride

CAS: 61881-19-4

Formula: C₈H₅ClF₃N

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 207.58

Ref: 3B-T2547

2,2,2-Trifluoro-N-phenylacetimidoyl chloride

CAS: 61881-19-4

Formula: C₈H₅ClF₃N

Purity: 97%

Color and Shape: Solid

Molecular weight: 207.5802

Ref: IN-DA003F7E

2,2,2-Trifluoro-N-phenylacetimidoyl chloride

CAS: 61881-19-4

2,2,2-Trifluoro-N-phenylacetimidoyl chloride

Purity: 98%

Molecular weight: 207.5802g/mol

Ref: 54-PC51008

2,2,2-Trifluoro-N-phenylacetimidoyl chloride

CAS: 61881-19-4

2,2,2-Trifluoro-N-phenylacetimidoyl chloride reacts with hemi-acetals to form an N-phenyltrifluoroacetimidate glycosyl donor. This donor was used recently to couple selectively with the primary-OH of a fructopyranosyl acceptor, containing a free anomeric hydroxyl group. The fructopyranosyl acceptor in-turn was converted to a donor. A novel hexa-fructopyranoside oligosaccharide was synthesized by further fructosyl-elongations.

Formula: C₈H₅ClF₃N

Purity: Min. 98 Area-%

Color and Shape: Colorless Yellow Clear Liquid

Molecular weight: 207.58 g/mol

Ref: 3D-FT45365

2,​2,​2-​Trifluoro-​N-​phenylacetimidoyl Chloride

Controlled Product

CAS: 61881-19-4

Applications 2,​2,​2-​Trifluoro-​N-​phenylacetimidoyl Chloride can be used as reactant/reagent in synthesis of oligo-fructopyranoside with difructopyranosyl N-phenyltrifluoroacetimidate donor via regioselective glycosylation.
References Zhang, H., et al.: Carbohyd Res, 448, 6, 2017

Formula: C₈H₅ClF₃N

Color and Shape: Neat

Molecular weight: 207.58

Ref: TR-T792605

2,2,2-Trifluoro-N-phenylacetimidoyl chloride

CAS: 61881-19-4

Formula: C₈H₅ClF₃N

Purity: 98%

Molecular weight: 207.58

Ref: 10-F546987