CAS 6192-62-7

Spirosolan-3-ol, hydrochloride (1:1), (3β,5α,22β,25S)-

Description:

Spirosolan-3-ol, hydrochloride (1:1), with the CAS number 6192-62-7, is a chemical compound characterized by its unique spirocyclic structure, which includes a steroid-like framework. This compound features a hydroxyl group (-OH) at the 3-position, contributing to its classification as an alcohol. The presence of the hydrochloride indicates that it is a salt formed with hydrochloric acid, enhancing its solubility in water and making it suitable for various applications, particularly in pharmaceutical formulations. The stereochemistry of the compound, denoted by the (3β,5α,22β,25S) configuration, suggests specific spatial arrangements of its atoms, which can influence its biological activity and interactions with other molecules. Generally, compounds like spirosolan-3-ol are studied for their potential therapeutic effects, including anti-inflammatory or analgesic properties, although specific biological activities would require further investigation. As with many chemical substances, safety and handling precautions are essential due to potential toxicity or reactivity.

Formula: C₂₇H₄₅NO₂·ClH

InChI: InChI=1S/C27H45NO2.ClH/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4;/h16-24,28-29H,5-15H2,1-4H3;1H/t16-,17-,18-,19-,20+,21-,22-,23-,24-,25-,26-,27-;/m0./s1

InChI key: InChIKey=SXXHVPYRDFJKPG-VXJLCZPPSA-N

SMILES: C[C@@H]1[C@@]2(O[C@@]3([C@]1([C@]4(C)[C@@](C3)([C@]5([C@](CC4)([C@]6(C)[C@@](CC5)(C[C@@H](O)CC6)[H])[H])[H])[H])[H])[H])CC[C@H](C)CN2.Cl

Synonyms:

• Spirosolan-3-ol, hydrochloride, (3β,5α,22β,25S)-
• 5α-Tomatidin-3β-ol, hydrochloride
• Tomatidin hydrochloride
• Spirosolan-3-ol, hydrochloride (1:1), (3β,5α,22β,25S)-
• Tomatidine hydrochloride

Tomatidine hydrochloride

CAS: 6192-62-7

Formula: C₂₇H₄₆ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 452.1126

Ref: IN-DA00EB5M

Tomatidine hydrochloride

CAS: 6192-62-7

Formula: C₂₇H₄₅NO₂·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 452.11

Ref: 7W-GP3515

TOMATIDINE HYDROCHLORIDE

CAS: 6192-62-7

TOMATIDINE HYDROCHLORIDE

Purity: ≥95%

Molecular weight: 452.11g/mol

Ref: 54-BUP16403

Tomatidine HCl

CAS: 6192-62-7

Formula: C₂₇H₄₆ClNO₂

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 452.12

Ref: BP-BP1725

TOMATIDINE HYDROCHLORIDE

CAS: 6192-62-7

Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.

Formula: C₂₇H₄₆ClNO₂

Purity: 99.75% - ≥95%

Color and Shape: Solid

Molecular weight: 452.11

Ref: TM-T4592

Tomatidine hydrochloride

CAS: 6192-62-7

Natural alkaloid

Formula: C₂₇H₄₅NO₂HCl

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 452.12

Ref: 5G-80003

Tomatidine Hydrochloride ( >85%)

Controlled Product

CAS: 6192-62-7

Applications A steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine.Tomatidine protects against muscle atrophy and boosting muscle growth (see also Ursolic Acid U850100).
References Watkins, D.N., et al.: Nature, 422, 313 (2003); Chem. and Eng. News p 27, May 5 (2014)

Formula: C₂₇H₄₅NO₂·xHCl

Purity: >85%

Color and Shape: Light Beige Powder

Molecular weight: 452.11

Ref: TR-T538500

Tomatidine hydrochloride

CAS: 6192-62-7

Tomatidine is a steroidal alkaloid found in the skins of unripe tomatoes. An LPS-stimulated macrophage model of inflammation was used to investigate the anti-inflammatory effects of tomatidine and it was found that the alkaloid could decrease inducible nitric oxide synthase and cyclooxygenase-2 expression through suppression of I-kappa B alpha phosphorylation. Thus it may be possible that Tomatidine can be developed as a useful agent for the chemoprevention of cancer or inflammatory diseases. When incorporated into growth media (agar) at 0.3 mM, tomatine and tomatidine inhibited the growth of three fungal bioherbicidal phytopathogens.

Formula: C₂₇H₄₅NO₂•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 452.11 g/mol

Ref: 3D-FT65189