CAS 61926-22-5
:Ethidium homodimer
Description:
Ethidium homodimer, with the CAS number 61926-22-5, is a fluorescent intercalating agent commonly used in molecular biology, particularly in the visualization of nucleic acids. This compound is characterized by its ability to bind to double-stranded DNA, resulting in a significant increase in fluorescence upon intercalation. Ethidium homodimer is typically utilized in applications such as gel electrophoresis, where it helps to stain DNA for detection under UV light. Its structure features a planar, polycyclic aromatic system that facilitates intercalation between base pairs of DNA. Importantly, this compound is membrane-impermeable, which means it can only penetrate cells with compromised membranes, making it useful for distinguishing between live and dead cells in assays. Ethidium homodimer is often employed in conjunction with other dyes to enhance the specificity and sensitivity of nucleic acid detection. However, it is essential to handle this compound with care, as it is considered a mutagen and can pose health risks if not managed properly in laboratory settings.
Formula:C46H48N8·2ClH·2Cl
InChI:InChI=1S/C46H46N8.4ClH/c47-33-13-17-37-39-19-15-35(49)29-43(39)53(45(41(37)27-33)31-9-3-1-4-10-31)25-7-21-51-23-24-52-22-8-26-54-44-30-36(50)16-20-40(44)38-18-14-34(48)28-42(38)46(54)32-11-5-2-6-12-32;;;;/h1-6,9-20,27-30,49-52H,7-8,21-26,47-48H2;4*1H
InChI key:InChIKey=ZKAJUKABUUJRLB-UHFFFAOYSA-N
SMILES:C(CCNCCNCCC[N+]=1C(=C2C(=C3C1C=C(N)C=C3)C=CC(N)=C2)C4=CC=CC=C4)[N+]=5C(=C6C(=C7C5C=C(N)C=C7)C=CC(N)=C6)C8=CC=CC=C8.[Cl-].Cl
Synonyms:- 5,5'-(1,2-Ethanediylbis(imino-3,1-propanediyl))bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
- 5,5'-(4,7-Diazadecamethylene)-bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
- 5,5'-(Ethylenebis(iminotrimethylene))bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
- EthD 1
- Ethidium homodimer 1
- Phenanthridinium, 5,5'-(1,2-ethanediylbis(imino-3,1-propanediyl)bis(3,8-diamino-6-phenyl-, dichloride, dihydrochloride
- Phenanthridinium, 5,5′-[1,2-ethanediylbis(imino-3,1-propanediyl)]bis[3,8-diamino-6-phenyl-, chloride, hydrochloride (1:2:2)
- Phenanthridinium, 8-Amino-3-Ammonio-5-[3-[[2-[[3-(3,8-Diamino-6-Methyl-5-Phenanthridiniumyl)Propyl]Amino]Ethyl]Amino]Propyl]-6-Phenyl-, Chloride, Hydrochloride (1:2:2)
- Ethidium homodimer
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Found 4 products.
EthD-1
CAS:<p>EthD-1 (Ethidium homodimer) is a high-affinity fluorescent nucleic acid dye that emits red fluorescence upon binding to DNA or RNA, Ex/Em=528/617 nm.</p>Formula:C46H50Cl4N8Color and Shape:SolidMolecular weight:856.76Ethidium homodimer I solution
CAS:Controlled ProductFormula:C46H48N8•2Cl•2HClColor and Shape:NeatMolecular weight:712.93+2(35.45)+2(36.46)



