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CAS 61926-22-5

:

Ethidium homodimer

Description:
Ethidium homodimer, with the CAS number 61926-22-5, is a fluorescent intercalating agent commonly used in molecular biology, particularly in the visualization of nucleic acids. This compound is characterized by its ability to bind to double-stranded DNA, resulting in a significant increase in fluorescence upon intercalation. Ethidium homodimer is typically utilized in applications such as gel electrophoresis, where it helps to stain DNA for detection under UV light. Its structure features a planar, polycyclic aromatic system that facilitates intercalation between base pairs of DNA. Importantly, this compound is membrane-impermeable, which means it can only penetrate cells with compromised membranes, making it useful for distinguishing between live and dead cells in assays. Ethidium homodimer is often employed in conjunction with other dyes to enhance the specificity and sensitivity of nucleic acid detection. However, it is essential to handle this compound with care, as it is considered a mutagen and can pose health risks if not managed properly in laboratory settings.
Formula:C46H48N8·2ClH·2Cl
InChI:InChI=1S/C46H46N8.4ClH/c47-33-13-17-37-39-19-15-35(49)29-43(39)53(45(41(37)27-33)31-9-3-1-4-10-31)25-7-21-51-23-24-52-22-8-26-54-44-30-36(50)16-20-40(44)38-18-14-34(48)28-42(38)46(54)32-11-5-2-6-12-32;;;;/h1-6,9-20,27-30,49-52H,7-8,21-26,47-48H2;4*1H
InChI key:InChIKey=ZKAJUKABUUJRLB-UHFFFAOYSA-N
SMILES:C(CCNCCNCCC[N+]=1C(=C2C(=C3C1C=C(N)C=C3)C=CC(N)=C2)C4=CC=CC=C4)[N+]=5C(=C6C(=C7C5C=C(N)C=C7)C=CC(N)=C6)C8=CC=CC=C8.[Cl-].Cl
Synonyms:
  • 5,5'-(1,2-Ethanediylbis(imino-3,1-propanediyl))bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
  • 5,5'-(4,7-Diazadecamethylene)-bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
  • 5,5'-(Ethylenebis(iminotrimethylene))bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
  • EthD 1
  • Ethidium homodimer 1
  • Phenanthridinium, 5,5'-(1,2-ethanediylbis(imino-3,1-propanediyl)bis(3,8-diamino-6-phenyl-, dichloride, dihydrochloride
  • Phenanthridinium, 5,5′-[1,2-ethanediylbis(imino-3,1-propanediyl)]bis[3,8-diamino-6-phenyl-, chloride, hydrochloride (1:2:2)
  • Phenanthridinium, 8-Amino-3-Ammonio-5-[3-[[2-[[3-(3,8-Diamino-6-Methyl-5-Phenanthridiniumyl)Propyl]Amino]Ethyl]Amino]Propyl]-6-Phenyl-, Chloride, Hydrochloride (1:2:2)
  • Ethidium homodimer
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Found 4 products.
  • Ethidium homodimer

    CAS:
    Formula:C46H50Cl4N8
    Purity:90%
    Molecular weight:856.7548

    Ref: IN-DA00E97X

    1mg
    To inquire
  • Ethidium homodimer I

    CAS:
    Purity:≥ 90.0%
    Color and Shape:Red to violet liquid
    Molecular weight:856.75

    Ref: 7W-GT0540

    1mg
    475.00€
    5mg
    1,155.00€
    10mg
    2,017.00€
  • EthD-1

    CAS:
    <p>EthD-1 (Ethidium homodimer) is a high-affinity fluorescent nucleic acid dye that emits red fluorescence upon binding to DNA or RNA, Ex/Em=528/617 nm.</p>
    Formula:C46H50Cl4N8
    Color and Shape:Solid
    Molecular weight:856.76
  • Ethidium homodimer I solution

    Controlled Product
    CAS:
    Formula:C46H48N8•2Cl•2HCl
    Color and Shape:Neat
    Molecular weight:712.93+2(35.45)+2(36.46)

    Ref: TR-E890715

    50mg
    14,624.00€