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CAS 61932-66-9

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de-N-sulfated heparin sodium

Description:
De-N-sulfated heparin sodium is a chemically modified form of heparin, a naturally occurring glycosaminoglycan that plays a crucial role in various biological processes, including anticoagulation. This substance is characterized by the removal of sulfate groups from the heparin structure, which alters its biological activity and pharmacological properties. De-N-sulfated heparin sodium retains some of the structural features of heparin, such as its linear polysaccharide chain, but exhibits reduced anticoagulant activity compared to its sulfated counterpart. It is often used in research settings to study the interactions of heparin with proteins and other biomolecules, as well as in the development of drug delivery systems. The modification of heparin to create de-N-sulfated heparin sodium can influence its solubility, binding affinity, and overall efficacy in various applications. As with other heparin derivatives, safety and efficacy must be evaluated in any therapeutic context, and its use is subject to regulatory oversight.
Formula:(C26H40N2O31S3)n
Synonyms:
  • Heparin, N-desulfated
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