CAS 61951-99-3

Tixocortol

Description:

Tixocortol, with the CAS number 61951-99-3, is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to modulate the immune response and reduce inflammation, making it effective in treating various allergic and inflammatory conditions. Tixocortol is often utilized in dermatological formulations, particularly for skin disorders such as eczema and dermatitis. The compound exhibits a relatively high affinity for glucocorticoid receptors, which contributes to its therapeutic effects. Additionally, it has a favorable pharmacokinetic profile, allowing for effective topical application with minimal systemic absorption. As with other corticosteroids, potential side effects may include skin thinning, irritation, or systemic effects with prolonged use. Overall, Tixocortol serves as a valuable option in the management of inflammatory conditions, particularly in topical formulations where localized treatment is desired.

Formula: C₂₁H₃₀O₄S

InChI: InChI=1S/C21H30O4S/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-26)20(15,2)10-16(23)18(14)19/h9,14-16,18,23,25-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key: InChIKey=YWDBSCORAARPPF-VWUMJDOOSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CS)=O)O)[H]

Synonyms:

• (11Beta)-11,17-Dihydroxy-21-Sulfanylpregn-4-Ene-3,20-Dione
• (11β)-11,17-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione
• 11beta,17-Dihydroxy-21-mercapto-4-pregnen-3,20-dion
• Cortisol 21-thiol
• Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-mercapto-, (11beta)-
• Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-mercapto-, (11β)-
• Progesterone, 11β,17-dihydroxy-21-mercapto-
• Tixocortol [INN:BAN]
• Tixocortolum
• Tixocortolum [INN-Latin]
• Tixocortol

Tixocortol

CAS: 61951-99-3

Formula: C₂₁H₃₀O₄S

Molecular weight: 378.53

Ref: 4Z-T-259001

Tixocortol

Controlled Product

CAS: 61951-99-3

Stability Hygroscopic
Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.
References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),

Formula: C₂₁H₃₀O₄S

Color and Shape: Neat

Molecular weight: 378.53

Ref: TR-T447490

Tixocortol

Controlled Product

CAS: 61951-99-3

Tixocortol is a corticosteroid that has been used for the treatment of bowel disease, skin cancer, and allergic symptoms. Tixocortol is a pivalate ester of hydrocortisone. This type of steroid is stable in the presence of air and light. It also has anti-inflammatory properties and may be used to treat inflammatory bowel disease or allergic symptoms. Tixocortol is not active against bacteria but can inhibit their growth by competing with other antibiotics for binding to the cell wall. Tixocortol has been shown to bind to glucocorticoid receptors, which are involved in regulating inflammation and immune responses.

Formula: C₂₁H₃₀O₄S

Purity: Min. 95%

Molecular weight: 378.5 g/mol

Ref: 3D-LCA95199