CAS 620-13-3

3-Methylbenzyl bromide

Description:

3-Methylbenzyl bromide, also known as meta-tolyl bromide, is an organic compound characterized by a bromine atom attached to a benzyl group that has a methyl substituent in the meta position. Its molecular formula is C9H11Br, and it features a benzene ring with a methyl group and a bromomethyl group. This compound is typically a colorless to pale yellow liquid with a distinctive aromatic odor. It is moderately soluble in organic solvents like ether and chloroform but has limited solubility in water. 3-Methylbenzyl bromide is primarily used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It can undergo various chemical reactions, including nucleophilic substitution and electrophilic aromatic substitution, making it a versatile building block in synthetic chemistry. As with many brominated compounds, it should be handled with care due to potential toxicity and environmental concerns. Proper safety measures, including the use of personal protective equipment, are recommended when working with this substance.

Formula: C₈H₉Br

InChI: InChI=1S/C8H9Br/c1-7-3-2-4-8(5-7)6-9/h2-5H,6H2,1H3

InChI key: InChIKey=FWLWTILKTABGKQ-UHFFFAOYSA-N

SMILES: C(Br)C1=CC(C)=CC=C1

Synonyms:

• 1-(Bromomethyl)-3-methylbenzene
• 3-(Bromomethyl)toluene
• 3-Methylbenzyl bromide
• Benzene, 1-(bromomethyl)-3-methyl-
• NSC 60146
• m-Methylbenzyl bromide
• m-Xylene, α-bromo-
• m-Xylyl bromide
• α-Bromo-m-xylene
• alpha-Bromo-m-xylene

α-Bromo-m-xylene

CAS: 620-13-3

Formula: C₈H₉Br

Purity: >90.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 185.06

Ref: 3B-B1010

α-Bromo-m-xylene

CAS: 620-13-3

Formula: C₈H₉Br

Purity: >98.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 185.06

Ref: 3B-B3585

3-Methylbenzyl bromide, 97%

CAS: 620-13-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₉Br

Purity: 97%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 185.06

Ref: 02-B24731

3-Methylbenzyl bromide

CAS: 620-13-3

3-Methylbenzyl bromide

Formula: C₈H₉Br

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 185.06g/mol

Ref: 54-OR6442

3-Methylbenzyl Bromide

CAS: 620-13-3

Formula: C₈H₉Br

Molecular weight: 185.06

Ref: 4Z-B-139072

1-(Bromomethyl)-3-methylbenzene

CAS: 620-13-3

Purity: 98.0%

Color and Shape: Liquid

Molecular weight: 185.06399536132812

Ref: 10-F067812

3-(Bromomethyl)toluene

Controlled Product

CAS: 620-13-3

Applications 3-(Bromomethyl)toluene is used to prepare TNF-​α converting enzyme (TACE) converting enzyme inhibitors. It is also used to synthesize chromen-4-ones as DNA-dependent protein kinase inhibitors.
E0
References Letavic, M., et al.: Bioorg. Med. Chem. Lett., 12, 1387 (2002); Hardcastle, I., et al.: J. Med. Chem., 48, 7829 (2005)

Formula: C₈H₉Br

Color and Shape: Neat

Molecular weight: 185.06

Ref: TR-B687610

3-Methylbenzyl Bromide

CAS: 620-13-3

Formula: C₈H₉Br

Molecular weight: 185.06

Ref: ST-EA-CP-M70019

3-Methylbenzyl Bromide

CAS: 620-13-3

Formula: C₈H₉Br

Purity: 95%

Color and Shape: Liquid

Molecular weight: 185.0611

Ref: IN-DA003JQT