CAS 62025-49-4

Ginsenoside F2

Description:

Ginsenoside F2 is a natural compound classified as a triterpenoid saponin, primarily derived from ginseng, particularly Panax ginseng. It is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. Ginsenoside F2 exhibits a complex molecular structure characterized by a steroid-like backbone with multiple hydroxyl groups, contributing to its biological activity. The compound is typically found in the form of a white to off-white powder and is soluble in organic solvents such as ethanol and methanol, but less soluble in water. Its mechanism of action is believed to involve modulation of various signaling pathways, which may enhance cellular health and resilience. Research into Ginsenoside F2 continues to explore its therapeutic potential in various health conditions, including cardiovascular diseases and neurodegenerative disorders. As with many natural products, the efficacy and safety of Ginsenoside F2 depend on factors such as dosage, formulation, and individual patient characteristics, necessitating further clinical studies to establish its role in medicine.

Formula: C₄₂H₇₂O₁₃

InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,55-37-35(51)33(49)31(47)25(20-44)53-37)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1

InChI key: InChIKey=SWIROVJVGRGSPO-JBVRGBGGSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)CC3)[H])(C[C@@H](O)[C@]5([C@@]2(C)CC[C@@]5([C@@](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)(CCC=C(C)C)C)[H])[H])[H]

Synonyms:

• (3β,12β)-12-Hydroxydammar-24-ene-3,20-diyl bis-β-<span class="text-smallcaps">D</span>-glucopyranoside
• 3-O-Glucosylginsenoside C K
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Dammarane,b-D-glucopyranoside deriv.
• Ginsenoside F2
• Ginsenoside F₂
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (3β,12β)-12-hydroxydammar-24-ene-3,20-diyl bis-
• β-D-Glucopyranoside, (3β,12β)-12-hydroxydammar-24-ene-3,20-diyl bis-
• (3β,12β)-12-Hydroxydammar-24-ene-3,20-diyl bis-β-D-glucopyranoside

Ginsenoside F2

CAS: 62025-49-4

Ginsenoside F2

Purity: ≥98%

Molecular weight: 785.01g/mol

Ref: 54-BUP07509

20-(S)-Ginsenoside F2

CAS: 62025-49-4

Ref: 7W-GC1949

Ginsenoside F2

CAS: 62025-49-4

Formula: C₄₂H₇₂O₁₃

Purity: >95.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 785.03

Ref: 3B-G0581

Ginsenoside F2

CAS: 62025-49-4

Ginsenoside F2 has the anti-cancer activity, it induces apoptosis in breast cancer stem cells (CSCs) by activating the intrinsic apoptotic pathway and mitochondrial dysfunction, also induces the formation of acidic vesicular organelles, recruitment of GFP-LC3-II to autophagosomes, and elevation of Atg-7 levels, suggests that F2 initiates an autophagic progression in breast CSCs.

Formula: C₄₂H₇₂O₁₃

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 785.025

Ref: BP-BP0654

Ginsenoside F2

CAS: 62025-49-4

Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.

Formula: C₄₂H₇₂O₁₃

Purity: 99.04% - 99.3%

Color and Shape: Solid

Molecular weight: 785.01

Ref: TM-T3916

20-(S)-Ginsenoside F2

CAS: 62025-49-4

20-(S)-Ginsenoside F2 is a bioactive compound isolated from the roots of Panax ginseng, a plant renowned for its diverse pharmacological properties. As a saponin glycoside, it is derived through the enzymatic hydrolysis of major ginsenosides like Rb1. The compound functions primarily through modulating various cellular pathways, including apoptosis, autophagy, and inflammation via its interaction with membrane receptors and intracellular signaling molecules.

Formula: C₄₂H₇₂O₁₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 785.01 g/mol

Ref: 3D-OG13740

20(S)-Ginsenoside F2

Controlled Product

CAS: 62025-49-4

Stability Hygroscopic
Applications Ginsenoside F2 is a bioactive metabolite of the ginsenoside component of Panax ginseng with the ability to regulate element-binding protein cleavage activating protein and transforming growth factor-β pathways. This control over apoptosis can lead to a control over hair growth and hair loss in mammals.
References Shin, H. et al.: Biol. Pharm. Bull., 37, 755 (2014); Shin, H. et al.: Eur. J. Pharm., 730, 82 (2014);

Formula: C₄₂H₇₂O₁₃

Color and Shape: Neat

Molecular weight: 785.01

Ref: TR-G387560

GINSENOSIDE F2

CAS: 62025-49-4

Formula: C₄₂H₇₂O₁₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 785.0133

Ref: IN-DA00EBH6