CAS 6205-08-9

N-Acetyl-L-ornithine

Description:

N-Acetyl-L-ornithine is a derivative of the amino acid ornithine, characterized by the addition of an acetyl group to the nitrogen atom of the amino group. It is a white to off-white crystalline powder that is soluble in water and exhibits a slightly acidic to neutral pH. This compound plays a significant role in the urea cycle, where it participates in the synthesis of arginine and is involved in various metabolic processes. N-Acetyl-L-ornithine is often utilized in biochemical research and has potential applications in the fields of nutrition and medicine, particularly in studies related to metabolic disorders and amino acid metabolism. Its molecular formula reflects its structure, containing carbon, hydrogen, nitrogen, and oxygen atoms. Additionally, it is important to handle this compound with care, following appropriate safety guidelines, as with any biochemical substance. Overall, N-Acetyl-L-ornithine serves as an important compound in both physiological functions and research applications.

Formula: C₇H₁₄N₂O₃

InChI: InChI=1/C7H14N2O3/c1-5(10)9-6(7(11)12)3-2-4-8/h6H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t6-/m0/s1

InChI key: InChIKey=JRLGPAXAGHMNOL-LURJTMIESA-N

SMILES: [C@@H](NC(C)=O)(C(O)=O)CCCN

Synonyms:

• (2S)-2-Acetamido-5-aminopentanoic acid
• (2S)-5-Amino-2-acetamidopentanoic acid
• <span class="text-smallcaps">L</span>-Ornithine, N²-acetyl-
• Ac-Orn-OH
• N-Acetyl-<span class="text-smallcaps">L</span>-ornithine
• N-Acetylornithine
• N²-Acetyl-<span class="text-smallcaps">L</span>-ornithine
• N^α-Acetyl-<span class="text-smallcaps">L</span>-ornithine
• N^α-Acetylornithine
• N~2~-acetyl-L-ornithine
• Ornithine, N²-acetyl-
• Ornithine, N²-acetyl-, <span class="text-smallcaps">L</span>-
• N2-Acetyl-L-ornithine
• Ornithine, N2-acetyl-
• L-Ornithine, N2-acetyl-
• Ornithine, N2-acetyl-, L-
• Nα-Acetyl-L-ornithine
• N-ACETYL-L-ORN
• N-ALPHA-ACETYL-L-ORNITHINE
• AC-ORNITHINE
• ACETYL-L-ORNITHINE
• N-A-acetyl-L-ornithine crystalline
• Nα-Acetyl-L-ornithine≥ 98% (HPLC)

Ac-Orn-OH

CAS: 6205-08-9

Bachem ID: 4002042.

Formula: C₇H₁₄N₂O₃

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 174.2

Ref: 01-4002042

N-α-ACETYL-L-ORNITHINE

CAS: 6205-08-9

Formula: C₇H₁₄N₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 174.1977

Ref: IN-DA00EFXH

N-Acetyl-L-ornithine

CAS: 6205-08-9

Formula: C₇H₁₄N₂O₃

Purity: ≥ 95%

Color and Shape: White to off-white powder

Molecular weight: 174.20

Ref: 7W-GH0222

N-Acetylornithine

CAS: 6205-08-9

N-Acetylornithine

Purity: ≥95%

Molecular weight: 174.2g/mol

Ref: 54-BUP15903

N-α-Acetyl-L-Ornithine

CAS: 6205-08-9

N-α-Acetyl-L-Ornithine

Purity: 95%

Molecular weight: 174.20g/mol

Ref: 54-OR1014503

Nα-Acetyl-L-ornithine-5,5-d2

CAS: 6205-08-9

Formula: H₂NCD₂(CH₂)₂CH(NHCOCH₃)COOH

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 176.113

Ref: 3U-D7660

N-Acetylornithine

CAS: 6205-08-9

N-Acetylornithine is found in human blood plasma (avg. 1.1±0.4 μmol/L) and urine (~1 μmol/day).

Formula: C₇H₁₄N₂O₃

Purity: 99.86% - ≥95%

Color and Shape: Solid

Molecular weight: 174.2

Ref: TM-T5269

Nα-Acetyl-L-ornithine

Controlled Product

CAS: 6205-08-9

Formula: C₇H₁₄N₂O₃

Color and Shape: Off-White

Molecular weight: 174.2

Ref: TR-A187240

Nα-Acetyl-L-ornithine-d2

Controlled Product

CAS: 6205-08-9

Applications Nα-Acetyl-L-ornithine (AORN) is a substrate for the identification, differentiation and characterization of N(α)-acetyl-L-ornithine deacetylase(s) and of N-Acetyl-l-ornithine transcarbamylase(s) (AOTCase).
References McGregor, W., et al.: J. Am. Chem. Soc., 127, 14100 (2005); Morizono, H., et al.: J. Bacetriol., 188, 2974 (2006);

Formula: C₇D₂H₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 176.21

Ref: TR-A187242

Na-Acetyl-L-ornithine

CAS: 6205-08-9

Formula: C₇H₁₄N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 174.2

Ref: 10-F492660

N-α-Acetyl-L-ornithine

CAS: 6205-08-9

N-alpha-Acetyl-L-ornithine is an intermediate in the urea cycle that has been shown to be a potential biomarker for metabolic disorders. It has also been shown to inhibit glutamate synthesis and nitrogen oxidation by inhibiting arginase and nitric oxide synthase. N-alpha-Acetyl-L-ornithine is synthesized from L-arginine and acetyl coenzyme A, catalyzed by synthetases. The reaction requires ATP, magnesium ion, and a molecule of NADPH. This synthetic pathway can be monitored using high performance liquid chromatography (HPLC). N-alpha-Acetyl-L ornithine can be used as a precursor in the production of caproic acid, which is an important organic acid used in chemical biology.

Formula: C₇H₁₄N₂O₃

Purity: Min. 95%

Molecular weight: 174.2 g/mol

Ref: 3D-FA47655