CAS 62054-67-5

4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]-

Description:

4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]- is an organic compound characterized by its morpholine and nitrophenyl functional groups. It features a morpholine ring, which is a six-membered heterocyclic structure containing one nitrogen atom, contributing to its basicity and potential as a nucleophile. The compound also contains a nitro group (-NO2) and a trifluoromethyl group (-CF3) attached to a phenyl ring, which significantly influence its chemical reactivity and physical properties. The presence of the trifluoromethyl group enhances lipophilicity and can affect the compound's biological activity, making it of interest in medicinal chemistry. This substance may exhibit various properties such as solubility in organic solvents, and its stability can be influenced by the electronic effects of the substituents. Additionally, due to the presence of the nitro group, it may participate in electrophilic aromatic substitution reactions. Safety and handling precautions should be observed, as compounds with nitro groups can be sensitive and potentially hazardous.

Formula: C₁₁H₁₂F₃N₃O₃

Synonyms:

• THS044;THS 044
• 4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]-
• THS-044

THS-044

CAS: 62054-67-5

THS-044

Purity: ≥98%

Molecular weight: 291.23g/mol

Ref: 54-BUP04935

THS-044

CAS: 62054-67-5

THS-044 (N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine) binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activity

Formula: C₁₁H₁₂F₃N₃O₃

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 291.23

Ref: TM-T13925