CAS 621-42-1

3-Acetamidophenol

Description:

3-Acetamidophenol, also known as paracetamol or acetaminophen, is an organic compound characterized by its aromatic structure featuring an amide and hydroxyl functional group. It is a white crystalline solid that is soluble in water and exhibits a melting point typically around room temperature. The compound has a molecular formula of C8H9NO2 and a molecular weight of approximately 151.16 g/mol. 3-Acetamidophenol is widely recognized for its analgesic and antipyretic properties, making it a common ingredient in over-the-counter medications for pain relief and fever reduction. The compound acts primarily by inhibiting the enzyme cyclooxygenase, which plays a crucial role in the synthesis of prostaglandins, thereby reducing pain and inflammation. It is generally considered safe when used as directed, although excessive doses can lead to hepatotoxicity. Additionally, 3-acetamidophenol is stable under normal conditions but should be stored in a cool, dry place away from light to maintain its efficacy.

Formula: C₈H₉NO₂

InChI: InChI=1S/C8H9NO2/c1-6(10)9-7-3-2-4-8(11)5-7/h2-5,11H,1H3,(H,9,10)

InChI key: InChIKey=QLNWXBAGRTUKKI-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC(O)=CC=C1

Synonyms:

• 3-(Acetylamino)-1-hydroxybenzene
• 3-(Acetylamino)phenol
• 3-Hydroxyacetanilide
• Acetamide, N-(3-hydroxyphenyl)-
• Acetanilide, 3′-hydroxy-
• Bs 479
• Bs 749
• Metacetamol
• Metalid
• N-(3-hydroxyphenyl)acetamide
• N-Acetyl-3-hydroxyaniline
• N-Acetyl-m-aminophenol
• NSC 3990
• Pedituss
• Pyrapap
• Rystal
• m-(Acetylamino)phenol
• m-Acetamidophenol

3-Acetamidophenol, 98%

CAS: 621-42-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₉NO₂

Purity: 98%

Color and Shape: White to cream to pink to grey or pale yellow to pale orange to pale brown, Crystals or powder or crystalline powder

Molecular weight: 151.17

Ref: 02-A12764

3-Acetamidophenol

CAS: 621-42-1

Formula: C₈H₉NO₂

Purity: 98%

Color and Shape: Chunks,Crystalline Powder,Needles

Molecular weight: 151.165

Ref: 10-F100300

Metacetamol

CAS: 621-42-1

Metacetamol, a non-toxic acetaminophen derivative, is an OTC analgesic/antipyretic and synthesis intermediate.

Formula: C₈H₉NO₂

Purity: 99.76% - 99.90%

Color and Shape: Physical Description Light Gray Solid (Ntp 1992)

Molecular weight: 151.16

Ref: TM-T0914

Acetamide, N-(3-hydroxyphenyl)-

CAS: 621-42-1

Formula: C₈H₉NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 151.1626

Ref: IN-DA00IAZ3

Metacetamol

CAS: 621-42-1

Metacetamol

Purity: ≥98%

Molecular weight: 151.16g/mol

Ref: 54-BUP17849

3-Acetamidophenol, min. 98%

CAS: 621-42-1

Formula: C₈H₉NO₂

Purity: min. 98%

Color and Shape: White to off-white solid

Molecular weight: 151.17

Ref: 08-07-0074

3-Acetamidophenol

CAS: 621-42-1

Formula: C₈H₉NO₂

Purity: ≥ 98.0%

Color and Shape: White to off-white solid

Molecular weight: 151.17

Ref: 7W-GK4538

3'-Hydroxyacetanilide

CAS: 621-42-1

Formula: C₈H₉NO₂

Purity: >98.0%(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 151.17

Ref: 3B-H0188

N-(3-Hydroxyphenyl)acetamide (3-Acetamidophenol)

CAS: 621-42-1

Color and Shape: Neat

Ref: 86-MM0042.16

3-Acetamidophenol

CAS: 621-42-1

3-Acetamidophenol

Formula: C₈H₉NO₂

Purity: ≥95%

Color and Shape: pale yellow solid

Molecular weight: 151.16g/mol

Ref: 54-OR27724

3-Acetamidophenol

Controlled Product

CAS: 621-42-1

Applications 3-Acetamidophenol is the ortho-regioisomer of Acetaminophen (A161220), an over-the-counter analgesic and antipyretic agent (1,2).
References (1) Queiroz, L.M., et al.: Chem. BIol. Drug. Design., 80, 100 (2012) (2) Harrelson, J. P., et al.: Drug. Metabolism. Disposit., 40, 1460 (2012)

Formula: C₈H₉NO₂

Color and Shape: Off-White To Light Brown

Molecular weight: 151.1626

Ref: TR-A158505

3-Acetamidophenol

CAS: 621-42-1

Formula: C₈H₉NO₂

Molecular weight: 151.17

Ref: ST-EA-CP-M11036