CAS 62129-44-6: N-tert-Butoxycarbonyl-4-iodo-L-phenylalanine
Description:N-tert-Butoxycarbonyl-4-iodo-L-phenylalanine, commonly referred to as Boc-4-iodo-L-Phe, is an amino acid derivative characterized by the presence of a tert-butoxycarbonyl (Boc) protecting group and an iodine atom at the para position of the phenyl ring. This compound is typically used in peptide synthesis, particularly in the formation of peptides where selective protection of the amino group is required. The Boc group enhances the stability of the amino acid during synthetic procedures and can be removed under mild acidic conditions. The iodine substituent can facilitate further reactions, such as nucleophilic substitutions or coupling reactions, making it a versatile building block in organic synthesis. The compound is generally solid at room temperature and is soluble in organic solvents, which aids in its handling and application in laboratory settings. Its molecular structure contributes to its reactivity and utility in various chemical transformations, particularly in the field of medicinal chemistry and peptide research.
Formula:C14H18INO4
InChI:InChI=1S/C14H18INO4/c1-14(2,3)20-13(19)16-11(12(17)18)8-9-4-6-10(15)7-5-9/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)/t11-/m0/s1
InChI key:InChIKey=JZLZDBGQWRBTHN-NSHDSACASA-N
SMILES:O=C(OC(C)(C)C)NC(C(=O)O)CC1=CC=C(I)C=C1
- Synonyms:
- (S)-2-(tert-Butoxycarbonylamino)-3-(4-iodophenyl)propanoic acid
- <span class="text-smallcaps">L</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-4-iodo-
- Boc-L-4-Iodophenylalanine
- Boc-L-Phe(4-I)-OH
- Boc-Phe(4-I)-OH
- N-(tert-Butoxycarbonyl)-p-iodo-<span class="text-smallcaps">L</span>-phenylalanine
- N-BOC-4-Iodo-<span class="text-smallcaps">L</span>-phenylalanine
- N-[(1,1-Dimethylethoxy)carbonyl]-4-iodo-<span class="text-smallcaps">L</span>-phenylalanine
- N-tert-Butoxycarbonyl-4-iodo-<span class="text-smallcaps">L</span>-phenylalanine
- L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-4-iodo-
- See more synonyms
- N-BOC-4-Iodo-L-phenylalanine
- N-[(1,1-Dimethylethoxy)carbonyl]-4-iodo-L-phenylalanine
- N-(tert-Butoxycarbonyl)-p-iodo-L-phenylalanine
- N-tert-Butoxycarbonyl-4-iodo-L-phenylalanine