CAS 62160-23-0

2-amino-7-(beta-D-ribofuranosyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one

Description:

2-amino-7-(beta-D-ribofuranosyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, also known by its CAS number 62160-23-0, is a nucleoside analog that exhibits structural features characteristic of both purines and pyrimidines. This compound contains a pyrrolo[2,3-d]pyrimidine core, which is fused with a ribofuranosyl moiety, contributing to its biological activity. The presence of an amino group at the 2-position and the ribose sugar enhances its potential for interaction with biological macromolecules, particularly nucleic acids. This compound is of interest in medicinal chemistry and biochemistry due to its potential role as an antiviral or anticancer agent, as it may interfere with nucleic acid synthesis or function. Its solubility and stability in biological systems can vary, influencing its pharmacokinetic properties. Overall, the unique structural characteristics of this compound make it a subject of research in the development of therapeutic agents targeting various diseases.

Formula: C₁₁H₁₄N₄O₅

InChI: InChI=1/C11H14N4O5/c12-11-13-8-4(9(19)14-11)1-2-15(8)10-7(18)6(17)5(3-16)20-10/h1-2,5-7,10,16-18H,3H2,(H3,12,13,14,19)/t5-,6-,7-,10-/m1/s1

SMILES: c1cn(c2c1c(nc(=N)[nH]2)O)[C@H]1[C@@H]([C@@H]([C@@H](CO)O1)O)O

7-Deazaguanosine

CAS: 62160-23-0

Ref: 7W-GN6362

7-Deazaguanosine

CAS: 62160-23-0

Nucleoside Derivatives - 7-Deaza-purine nucleosides; Drugs and Inhibitors; Antiviral agent, anti-HCV

Formula: C₁₁H₁₄N₄O₅

Color and Shape: Solid

Molecular weight: 282.25

Ref: TM-TNU0180

7-Deazaguanosine

CAS: 62160-23-0

7-Deazaguanosine is a low energy analog of guanosine that has been shown to be activated by trifluoroacetic acid, which is a chemical reagent that can be used for the activation of nucleosides. 7-Deazaguanosine is used in the treatment of human serum and urine viruses such as hepatitis B virus, herpes simplex virus, and cytomegalovirus. The compound has also been shown to have receptor agonism activity on toll-like receptors. 7-Deazaguanosine has been shown to have antiviral effects against HIV and influenza A (H1N1). 7-Deazaguanosine binds at the viral receptor site and blocks the entry process into cells. This drug also stimulates macrophages to produce cytokines, which are proteins that regulate immune responses.

Formula: C₁₁H₁₄N₄O₅

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 282.26 g/mol

Ref: 3D-ND05752