CAS 622-59-3

p-Tolyl isothiocyanate

Description:

p-Tolyl isothiocyanate, with the CAS number 622-59-3, is an organic compound characterized by the presence of an isothiocyanate functional group attached to a para-tolyl group. It typically appears as a colorless to pale yellow liquid with a pungent odor, reminiscent of mustard oil. This compound is known for its reactivity, particularly in nucleophilic substitution reactions, due to the electrophilic nature of the isothiocyanate group. p-Tolyl isothiocyanate is soluble in organic solvents such as ethanol and ether but has limited solubility in water. It is often used in organic synthesis and as a reagent in various chemical reactions, including the synthesis of thioureas and other nitrogen-containing compounds. Additionally, it has applications in biological research, particularly in studies related to its potential anticancer properties and its role in the modulation of cellular processes. As with many isothiocyanates, it is important to handle p-tolyl isothiocyanate with care due to its potential irritant effects on the skin and respiratory system.

Formula: C₈H₇NS

InChI: InChI=1/C8H7NS/c1-7-2-4-8(5-3-7)9-6-10/h2-5H,1H3

InChI key: InChIKey=ABQKHKWXTUVKGF-UHFFFAOYSA-N

SMILES: N(=C=S)C1=CC=C(C)C=C1

Synonyms:

• 1-Isothiocyanato-4-methylbenzene
• 4-Methylphenyl isothiocyanate
• 4-Tolyl isothiocyanate
• Isothiocyanate De P-Tolyle
• Isothiocyanate, 4-Methylphenyl
• Isothiocyanic acid, p-tolyl ester
• Isotiocianato De P-Tolilo
• P-Tolyl Isothiocyanate
• p-Methylphenyl isothiocyanate
• p-Tolylisothiocyanat
• Benzene, 1-isothiocyanato-4-methyl-
• Benzene, 1-isothiocyanato-4-methyl-
• 4-METHYLPHENYL ISOTHIOCYANATE 99+%
• AKOS BBS-00004440
• ISOTHIOCYANIC ACID 4-METHYLPHENYL ESTER
• p-Tolylisothiocyanate,97%
• isothiocyanicacid,4-tolylester

p-Tolyl isothiocyanate, 97%

CAS: 622-59-3

p-Tolyl isothiocyanate has been used in the preparation of 6-[1-amino-3-(p-tolyl)-thiourea]-2-ethylbenzo[de]isoquinoline-1,3-dione. It is used as capping agent to cap the N-terminal ends of polypeptide. It is also used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product wa

Formula: C₈H₇NS

Purity: 97%

Color and Shape: Liquid, Clear colorless to yellow

Molecular weight: 149.21

Ref: 02-A11499

1-isothiocyanato-4-methylbenzene

CAS: 622-59-3

Formula: C₈H₇NS

Purity: 97%

Color and Shape: Solid

Molecular weight: 149.2129

Ref: IN-DA003LSG

4-Methylphenyl isothiocyanate

CAS: 622-59-3

4-Methylphenyl isothiocyanate

Purity: 98%

Molecular weight: 149.21g/mol

Ref: 54-OR30196

p-Tolyl Isothiocyanate

CAS: 622-59-3

Formula: C₈H₇NS

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Yellow powder to lump to clear liquid

Molecular weight: 149.21

Ref: 3B-I0393

4-Tolyl isothiocyanate

CAS: 622-59-3

Formula: C₈H₇NS

Purity: 97.0%

Color and Shape: Light yellow crystalline solid

Molecular weight: 149.21

Ref: 10-F001282

p-Tolyl isothiocyanate

CAS: 622-59-3

p-Tolyl isothiocyanate belongs to a class of compounds called isothiocyanates. It has been shown to have antibacterial activity against Gram-negative bacteria, including Escherichia coli and Pseudomonas aeruginosa. The compound inhibits the synthesis of bacterial proteins by binding to the amino groups on their ribosomes, which prevents the attachment of tRNA molecules and blocks protein synthesis. p-Tolyl isothiocyanate can be synthesized in two steps starting from 2-chlorobenzaldehyde and 3-methylthiopropionaldehyde. This molecule has also been shown to have antiadhesive effects against Streptococcus mutans, which are bacteria that cause tooth decay.

Formula: CH₃C₆H₄NCS

Purity: Min. 95%

Molecular weight: 149.21 g/mol

Ref: 3D-AAA62259