CAS 62252-26-0

7-amino-4-chloro-3-methoxy-1H-isochromen-1-one

Description:

7-Amino-4-chloro-3-methoxy-1H-isochromen-1-one is a chemical compound characterized by its unique structural features, which include an isoquinoline framework with specific functional groups. The presence of an amino group (-NH2) at the 7-position and a chloro group (-Cl) at the 4-position contributes to its reactivity and potential biological activity. The methoxy group (-OCH3) at the 3-position enhances its solubility and may influence its interaction with biological targets. This compound is often studied for its potential applications in pharmaceuticals, particularly in the development of drugs due to its structural similarity to other biologically active molecules. Its CAS number, 62252-26-0, allows for easy identification in chemical databases. The compound's properties, such as melting point, solubility, and spectral characteristics, are essential for understanding its behavior in various chemical environments and its potential uses in medicinal chemistry and other fields.

Formula: C₁₀H₈ClNO₃

InChI: InChI=1/C10H8ClNO3/c1-14-10-8(11)6-3-2-5(12)4-7(6)9(13)15-10/h2-4H,12H2,1H3

SMILES: COc1c(c2ccc(cc2c(=O)o1)N)Cl

Synonyms:

• 1H-2-Benzopyran-1-one, 7-amino-4-chloro-3-methoxy-
• 7-Amino-4-chloro-3-methoxy-isocoumarin
• 7-Amino-4-chloro-3-methoxy-1H-isochromen-1-one

7-Amino-4-chloro-3-methoxyisocoumarin

CAS: 62252-26-0

Formula: C₁₀H₈ClNO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 225.6284

Ref: IN-DA00EAIY

JLK6

CAS: 62252-26-0

JLK6

Purity: ≥95%

Molecular weight: 225.63g/mol

Ref: 54-BUP07243

JLK6

CAS: 62252-26-0

JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling

Formula: C₁₀H₈ClNO₃

Purity: 96.50%

Color and Shape: Solid

Molecular weight: 225.63

Ref: TM-T21890

JLK 6

Controlled Product

CAS: 62252-26-0

Stability Hygroscopic
Applications JLK 6 is an inhibitor of γ-secretase, selectively inhibits βAPP cleavage.

Formula: C₁₀H₈ClNO₃

Color and Shape: Neat

Molecular weight: 225.63

Ref: TR-J211985

JLK 6

CAS: 62252-26-0

JLK 6 is a protease inhibitor that inhibits the pancreatic enzyme trypsin. It is also a potent serine protease inhibitor and has been shown to inhibit the activity of cholinesterases. JLK 6 has been shown to inhibit endothelial cell proliferation, which may be due to its ability to prevent the synthesis of bioactive molecules such as nitric oxide and prostaglandins. In addition, JLK 6 is a competitive inhibitor of vitamin D3.

Formula: C₁₀H₈ClNO₃

Purity: Min. 95%

Molecular weight: 225.63 g/mol

Ref: 3D-MCA25226