CAS 62253-63-8

Epidermal Growth Factor

Description:

Epidermal Growth Factor (EGF) is a polypeptide growth factor that plays a crucial role in cell growth, proliferation, and differentiation. It is composed of 53 amino acids and is known for its ability to bind to the epidermal growth factor receptor (EGFR), initiating a cascade of cellular signaling pathways that promote various biological processes, including wound healing and tissue regeneration. EGF is produced by various tissues in the body and is particularly abundant in saliva and urine. Its stability is influenced by factors such as pH and temperature, and it is typically stored under controlled conditions to maintain its biological activity. EGF has applications in both research and clinical settings, particularly in dermatology and oncology, where it is used to enhance skin repair and as a potential therapeutic agent in cancer treatment. The CAS number 62253-63-8 uniquely identifies this substance in chemical databases, facilitating its study and application in scientific research.

Synonyms:

• EGF
• Human Oligopeptide-1
• Recombinant Human Epidermal Growth Factor
• Recombinant human epidermalgrowth factor

rec EGF (human)

CAS: 62253-63-8

approx. ED₅₀ ≤ 0.1 ng/mL Human EGF (urogastrone, nepidermin) is a polypeptide hormone which was first isolated from human urine. It is a potent mitogen for a variety of cultured cells, e.g. fibroblasts. In vivo, urogastrone may have a role in the maintenance of gastrointestinal homeostasis. Furthermore, EGF is used in wound healing.

Formula: C₂₇₀H₃₉₅N₇₃O₈₃S₇

Purity: ≥ 98%

Color and Shape: White

Molecular weight: 6216.01

Ref: 01-4030572

Human epidermal growth factor

CAS: 62253-63-8

Formula: C₂₇₀H₄₀₁N₇₃O₈₃S₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 6221.9672

Ref: IN-DA01EFAY

rHuEGF

CAS: 62253-63-8

rHuEGF

Molecular weight: 0.00g/mol

Ref: 54-BIE2417

Epidermal Growth Factor

CAS: 62253-63-8

EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.

Formula: C₂₇₀H₄₀₁N₇₃O₈₃S₇

Purity: 97.17%

Color and Shape: Solid

Molecular weight: 6222

Ref: TM-T8679

EGF (Human)

CAS: 62253-63-8

EGF is a growth factor that is secreted by many types of cells, including endocrine cells and immune cells. It binds to the EGF receptor on the surface of cells. Binding activates tyrosine kinase receptors, which in turn promote cell growth and division. EGF has been used as a research tool for investigating protein interactions and studying ion channels. It can also be used to study the role of EGF in cell biology and as an inhibitor to study protein-protein interactions.

Formula: C₂₇₀H₃₉₅N₇₃O₈₃S₇

Purity: Min. 95%

Molecular weight: 6,215.9 g/mol

Ref: 3D-PGR-4498-S

rec EGF (human)

CAS: 62253-63-8

Epidermal Growth Factor (EGF) is a human protein that is involved in the regulation of cell growth, differentiation and survival. Recombinant EGF is an antigen binding molecule that can be used as a cancer treatment. Recombinant EGF has been shown to stimulate cellular transformation by binding to the epidermal growth factor receptor. It also has been shown to inhibit the growth of breast cancer cells with the HER2 gene mutation. The molecular weight of rec EGF is approximately 25 kDa and is composed of 165 amino acids. Recombinant EGF can be used in immunoassays, as a model system for studying biological properties, or as an antibody production tool.

Formula: C₂₇₀H₃₉₅N₇₃O₈₃S₇

Purity: Min. 95%

Molecular weight: 6,215.93 g/mol

Ref: 3D-FR110126