CAS 62265-68-3

Quinfamide

Description:

Quinfamide is a chemical compound classified as an antimalarial agent, primarily used in the treatment of malaria caused by Plasmodium species. It is characterized by its unique chemical structure, which includes a quinoline moiety, contributing to its biological activity. Quinfamide exhibits a mechanism of action that involves interference with the parasite's metabolic processes, particularly affecting the heme detoxification pathway. This compound is known for its moderate efficacy against various strains of malaria, including those resistant to other treatments. In terms of physical properties, Quinfamide is typically a solid at room temperature, with specific solubility characteristics that may vary depending on the solvent used. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important for determining its therapeutic effectiveness and safety profile. As with many pharmaceuticals, potential side effects and contraindications should be considered when evaluating its use in clinical settings. Overall, Quinfamide represents a valuable option in the ongoing fight against malaria, particularly in regions where resistance to conventional treatments is prevalent.

Formula: C₁₆H₁₃Cl₂NO₄

InChI: InChI=1S/C16H13Cl2NO4/c17-14(18)15(20)19-7-1-3-10-9-11(5-6-12(10)19)23-16(21)13-4-2-8-22-13/h2,4-6,8-9,14H,1,3,7H2

InChI key: InChIKey=SBJGFIXQRZOVTO-UHFFFAOYSA-N

SMILES: C(C(Cl)Cl)(=O)N1C=2C(=CC(OC(=O)C3=CC=CO3)=CC2)CCC1

Synonyms:

• 1-(2,2-Dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl furan-2-carboxylate
• 1-(Dichloroacetyl)-1,2,3,4-Tetrahydroquinolin-6-Yl Furan-2-Carboxylate
• 1-(Dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl 2-furoate
• 2-Furancarboxylic acid, 1-(2,2-dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester
• 2-Furancarboxylic acid, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester
• 2-Furanearboxylic Acid 1-(Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl Ester
• 263-478-1
• 62265-68-3
• Amenide
• Amenox
• Win 40014

2-Furancarboxylic acid, 1-(2,2-dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester

CAS: 62265-68-3

Formula: C₁₆H₁₃Cl₂NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 354.1847

Ref: IN-DA0035K5

Quinfamide

CAS: 62265-68-3

Quinfamide

Purity: ≥98%

Molecular weight: 354.18g/mol

Ref: 54-BUP09241

Quinfamide

CAS: 62265-68-3

Formula: C₁₆H₁₃Cl₂NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 354.18

Ref: 4Z-Q-001001

Quinfamide

Controlled Product

CAS: 62265-68-3

Applications Quinfamide is an anti-amebic agent used to treat tropical parasitic infections.
References Slighter, R., et al.: Parasitol., 81, 157 (1980), Parthasarathy, P., et al.: Eur. J. Med. Chem., 28, 195 (1993), Padilla, N., et al.: Clin. Drug Invest., 20, 89 (2000),

Formula: C₁₆H₁₃Cl₂NO₄

Color and Shape: White To Light Beige

Molecular weight: 354.18

Ref: TR-Q670600

Quinfamide

CAS: 62265-68-3

Quinfamide is a polyunsaturated compound that contains a cevimeline hydrochloride molecule. It is used to treat bowel disease, usually in combination with other drugs. Quinfamide has been shown to have specific treatment effects on the symptoms of inflammatory bowel disease (IBD) when given at doses of 400-800 mg per day for up to 12 weeks. This drug can also be used as an analog for 5-membered heteroaryl compounds, such as benzalkonium chloride, which are also used to treat bowel disease. Quinfamide has been shown to have anti-inflammatory properties and may work by inhibiting fatty acid synthesis or by reducing the number of neutrophils in the gut.

Formula: C₁₆H₁₃Cl₂NO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 354.18 g/mol

Ref: 3D-FQ27375

Quinfamide

CAS: 62265-68-3

Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.

Formula: C₁₆H₁₃Cl₂NO₄

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 354.18

Ref: TM-T16705