CAS 6230-11-1

O-Methyl-L-tyrosine

Description:

O-Methyl-L-tyrosine, also known as 3-methoxy-L-tyrosine, is an amino acid derivative characterized by the presence of a methoxy group (-OCH3) attached to the aromatic ring of the tyrosine structure. This modification enhances its solubility and alters its biochemical properties compared to standard L-tyrosine. The compound is often utilized in biochemical research and studies related to neurotransmitter synthesis, as it can influence the production of catecholamines. O-Methyl-L-tyrosine is known to act as a competitive inhibitor of tyrosine hydroxylase, the enzyme responsible for converting L-tyrosine to L-DOPA, thereby affecting dopamine synthesis. It is typically found in a crystalline form and is soluble in polar solvents. The substance has potential applications in pharmacology and neurobiology, particularly in understanding the role of neurotransmitters in various physiological processes. As with many amino acid derivatives, its safety and efficacy in therapeutic contexts require careful evaluation through clinical studies.

Formula: C₁₀H₁₃NO₃

InChI: InChI=1/C10H13NO3/c1-14-8-4-2-7(3-5-8)6-9(11)10(12)13/h2-5,9H,6,11H2,1H3,(H,12,13)

InChI key: InChIKey=GEYBMYRBIABFTA-VIFPVBQESA-N

SMILES: C([C@@H](C(O)=O)N)C1=CC=C(OC)C=C1

Synonyms:

• (2S)-2-Amino-3-(4-methoxyphenyl)propanoic acid
• (S)-2-Amino-3-(4-methoxyphenyl)propanoic acid
• 4-Methoxy-L-phenylalanine
• <span class="text-smallcaps">L</span>-4-Methoxyphenylalanine
• <span class="text-smallcaps">L</span>-O-Methyltyrosine
• <span class="text-smallcaps">L</span>-Tyrosine methyl ether
• <span class="text-smallcaps">L</span>-Tyrosine, O-methyl-
• Alanine, 3-(p-methoxyphenyl)-, <span class="text-smallcaps">L</span>-
• H-Tyr(Me)-OH
• L-4-Methoxyphenylalanine
• NSC 30082
• O-Methyl-<span class="text-smallcaps">L</span>-tyrosine
• O-methyltyrosine
• p-Methoxy-<span class="text-smallcaps">L</span>-phenylalanine
• p-Methoxy-L-phenylalanine
• β-(4-Methoxyphenyl)-<span class="text-smallcaps">L</span>-alanine
• O-Methyl-L-tyrosine
• Alanine, 3-(p-methoxyphenyl)-, L-
• L-Tyrosine, O-methyl-
• (2S)-2-Amino-3-(4-methoxyphenyl)propionic acid
• (S)-2-AMINO-3-(4-METHOXY-PHENYL)-PROPIONIC ACID
• 4-METHOXY-PHE-OH
• L-4-METHOXYPHE
• 4-METHOXYPHENYLALANINE
• H-L-Tyr(Me)-OH
• (S)-α-Amino-4-methoxybenzenepropanoic acid
• H-4-METHOXY-PHE-OH
• L-4-MeO-Phe-OH
• TYROSINE(ME)-OH
• L-H-Tyr(Me)-OH
• H-P-METHOXY-PHE-OH
• P-METHOXYPHENYLALANINE
• (2R)-2-amino-3-(4-methoxyphenyl)propanoic acid
• L-TYROSINE-O-METHYL ETHER

O-Methyl-L-tyrosine

CAS: 6230-11-1

Formula: C₁₀H₁₃NO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 195.22

Ref: 3B-M2276

O-Methyl-L-tyrosine, 98%

CAS: 6230-11-1

O-Methyl-L-tyrosine, is used as a fine chemical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference h

Formula: C₁₀H₁₃NO₃

Purity: 98%

Molecular weight: 195.22

Ref: 02-H63096

H-Tyr(Me)-OH

CAS: 6230-11-1

Bachem ID: 4003985.

Formula: C₁₀H₁₃NO₃

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 195.22

Ref: 01-4003985

H-Tyr(Me)-OH

CAS: 6230-11-1

Formula: C₁₀H₁₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 195.2151

Ref: IN-DA003LNW

4-Methoxy-L-phenylalanine

CAS: 6230-11-1

4-Methoxy-L-phenylalanine

Purity: 98%

Molecular weight: 195.22g/mol

Ref: 54-OR927182

O-Methyl-L-tyrosine

CAS: 6230-11-1

Molecular weight: 195.22

Ref: 7W-GM3349

O-Methyl-L-tyrosine

CAS: 6230-11-1

O-Methyl-L-tyrosine is a non-protein amino acid that inhibits protein synthesis by preventing the formation of peptide bonds. It has been shown to be an effective inhibitor of methionyl and cysteyl synthetases, which are enzymes that synthesize proteins. O-Methyl-L-tyrosine has also been used in clinical studies to treat translation defects associated with Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA). This drug is a synthetic amino acid that is not found in nature. Its structure consists of two methyl groups bonded to the oxygen atom on the tyrosine side chain, making it more stable than L-tyrosine. OMT binds to the enzyme methionyl synthetase in its active site, preventing formation of peptide bonds during protein synthesis. In addition, this drug has been shown to inhibit methyltetrahydrofolate reductase, an enzyme involved

Formula: C₁₀H₁₃NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 195.22 g/mol

Ref: 3D-FM25869

4-Methoxy-phenylalanine

CAS: 6230-11-1

M03187 - 4-Methoxy-phenylalanine

Formula: C₁₀H₁₃NO₃

Purity: 98%

Color and Shape: Solid, White powder

Molecular weight: 195.218

Ref: 10-M03187

O-Methyl-L-tyrosine

Controlled Product

CAS: 6230-11-1

Applications A non-natural Phenylalanine (P319415) derivative.
References Paradisi, F., et al.: J. Biotechnol., 128, 408 (2007),

Formula: C₁₀H₁₃NO₃

Color and Shape: Neat

Molecular weight: 195.22

Ref: TR-M332675