CAS 62340-29-8

Oxyntomodulin

Description:

Oxyntomodulin is a peptide hormone that is primarily produced in the intestinal L-cells in response to food intake. It is a 37-amino acid molecule that shares structural similarities with glucagon and GLP-1 (glucagon-like peptide-1), playing a significant role in regulating appetite and energy balance. Oxyntomodulin has been shown to suppress appetite and increase energy expenditure, making it a subject of interest in obesity research and metabolic disorders. Its mechanism of action involves binding to the GLP-1 receptor and the glucagon receptor, which influences insulin secretion and glucose metabolism. Additionally, oxyntomodulin may have effects on gastric motility and the secretion of gastric acid. Due to its physiological effects, it has potential therapeutic applications in weight management and diabetes treatment. The CAS number 62340-29-8 uniquely identifies this compound in chemical databases, facilitating research and development in pharmacology and biochemistry.

Formula: Unspecified

Synonyms:

• Enteroglucagonoid
• Gut glucagon
• Glucagon, entero-
• Oxyntomodulin
• Enteroglucagon

Oxyntomodulin

CAS: 62340-29-8

GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.

Formula: C₁₉₂H₂₉₅N₅₉O₆₀S

Purity: 98%

Color and Shape: Solid

Molecular weight: 4421.86

Ref: TM-TP1976

Oxyntomodulin, Glucagon-37 (Porcine)

CAS: 62340-29-8

Oxyntomodulin, a peptide hormone made up of 37 amino acids, is produced and released from gut endocrine L-cells. It has the ability to regulate gastric acids secretion in the gastric oxyntic glands. Oxyntomodulin, Glucagon-37 (Porcine) product is avaiable in the Trifluoroacetate salt form and can be used as an inhibitor of gastric acid secretion and pancreatic enzyme secretion. It has also been shown to reduce food intake and increase energy expenditure in humans. Central injection of oxyntomodulin reduces food intake and weight gain in rodents, suggesting that oxyntomodulin signals food ingestion to hypothalamic appetite-regulating circuits.

Formula: C₁₉₂H₂₉₅N₅₉O₆₀S

Purity: Min. 95%

Molecular weight: 4,421.92 g/mol

Ref: 3D-PGL-3827-PI

Oxyntomodulin (porcine, bovine)

CAS: 62340-29-8

Oxyntomodulin is a peptide hormone that is used as a pharmacological treatment for diabetes. Oxyntomodulin is an analogue of glucagon, which belongs to the family of glucagon-like peptide-1 (GLP-1) agonists. Oxyntomodulin has been shown to improve glucose tolerance and increase insulin secretion in humans and animals. This drug has also been shown to decrease appetite and improve weight loss in overweight patients with type 2 diabetes. The physiological effects of oxyntomodulin are mediated by GLP-1 receptors on multiple organs, including the pancreas, liver, gut, adipose tissue, brain, heart, and kidneys. Oxyntomodulin also inhibits the activity of dipeptidyl peptidase IV (DPP-IV), which may have therapeutic benefits for type 2 diabetes by slowing gastric emptying and increasing satiety. The administration of oxyntomodulin leads to increased mitochondrial membrane potential in

Formula: C₁₉₂H₂₉₅N₅₉O₆₀S

Purity: Min. 95%

Molecular weight: 4,421.86 g/mol

Ref: 3D-MCA34029