CAS 6244-92-4

Lauroyl-CoA

Description:

Lauroyl-CoA, also known as lauroyl coenzyme A, is a fatty acyl-CoA derivative that plays a crucial role in lipid metabolism and biosynthesis. It is characterized by a long-chain fatty acid, specifically lauric acid, which consists of 12 carbon atoms. The structure of Lauroyl-CoA includes a coenzyme A moiety that facilitates its involvement in various biochemical reactions, particularly in the synthesis and degradation of fatty acids. This compound is typically found in cellular compartments such as the mitochondria and cytoplasm, where it participates in metabolic pathways, including fatty acid oxidation and the synthesis of complex lipids. Lauroyl-CoA is also important in the formation of membrane lipids and signaling molecules. Its activity is regulated by various enzymes, including acyl-CoA synthetases and acyltransferases, which modulate its availability and function in metabolic processes. Overall, Lauroyl-CoA is essential for maintaining cellular energy balance and lipid homeostasis.

Formula: C₃₃H₅₈N₇O₁₇P₃S

InChI: InChI=1S/C33H58N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40/h20-22,26-28,32,43-44H,4-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48)/t22-,26-,27-,28+,32-/m1/s1

InChI key: InChIKey=YMCXGHLSVALICC-GMHMEAMDSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCSC(CCCCCCCCCCC)=O)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Synonyms:

• Coenzyme A, S-dodecanoate
• Coenzyme A, S-laurate
• Coenzyme A, lauroyl-
• Dodecanethioic acid, S-ester with coenzyme A
• Dodecanoyl-coa
• Dodecanoyl-coenzyme A
• Lauroyl-coa
• Lauroyl-coenzyme A
• Lauryl coenzyme A
• Lauryl-CoA
• S-{(9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} dodecanethioate (non-preferred name)

Lauroyl-coenzyme A

CAS: 6244-92-4

Lauroyl-coenzyme A acts as an acyl carrier, involved in lipid metabolism, biosynthesis, and fatty acid transport.

Formula: C₃₃H₅₈N₇O₁₇P₃S

Color and Shape: Solid

Molecular weight: 949.84

Ref: TM-T32598

Dodecanoyl Coenzyme A K salt

CAS: 6244-92-4

Formula: C33H58N7O17P3S

Purity: >95%

Color and Shape: Solid

Molecular weight: 949.84

Ref: 48-19-1200

Lauroyl Coenzyme A, Free acid

CAS: 6244-92-4

Purity: 95%

Molecular weight: 949.282

Ref: 10-C300039

Lauroyl coenzyme A

CAS: 6244-92-4

Lauroyl CoA is a body-fat molecule that can be formed from acetyl-coenzyme A, which is an intermediate in the metabolism of fatty acids. It is used in analysis as a standard for enzyme activities and as a substrate for reactions involving enzymes with coenzyme A. Reaction mechanisms are determined using titration calorimetry and structural analyses are performed using analytical methods such as infrared spectroscopy and nuclear magnetic resonance spectroscopy. Lauroyl CoA is also used to study the effects of the protein toll-like receptor 4 on hepatic steatosis. The wild-type strain of Escherichia coli was used to measure the activity of bacterial synthetases containing lauroyl CoA.

Formula: C₃₃H₅₈N₇O₁₇P₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 949.84 g/mol

Ref: 3D-NL47197

Lauroyl coenzyme A potassium salt

CAS: 6244-92-4

Lauroyl coenzyme A potassium salt is a potent inhibitor of fatty acid synthase. It has the ability to inhibit the enzyme activity of fatty acid synthase in vitro, which belongs to the class of irreversible inhibitors. Lauroyl coenzyme A potassium salt inhibits the synthesis of fatty acids by inhibiting the enzyme activity of fatty acid synthase. This inhibitor also reversibly inhibits other enzymes with a similar mechanism, such as acetyl-coenzyme A carboxylase and phosphatidate phosphohydrolase. The reaction mechanism can be understood through titration calorimetry studies, demonstrating that lauroyl coenzyme A potassium salt binds to the active site of these enzymes and blocks access to substrates. The binding affinity is higher for wild type strains than for mutant strains, which may be due to differences in protein structure or other factors. Lauroyl coenzyme A potassium salt has been shown to have no effect on wild-type strains but inhibits polymer

Formula: C₃₃H₅₅N₇O₁₇P₃SK₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,064.11 g/mol

Ref: 3D-NL161093