CAS 625-99-0

1-Chloro-3-iodobenzene

Description:

1-Chloro-3-iodobenzene, with the CAS number 625-99-0, is an aromatic halogenated compound characterized by the presence of both chlorine and iodine substituents on a benzene ring. Specifically, the chlorine atom is located at the first position and the iodine atom at the third position relative to each other on the benzene ring, making it a meta-substituted compound. This structure contributes to its unique chemical properties, including its reactivity in nucleophilic substitution reactions, where the halogen atoms can be replaced by other nucleophiles. The compound is typically a colorless to pale yellow liquid or solid, depending on the temperature, and has moderate solubility in organic solvents. Its boiling and melting points are influenced by the halogen substituents, which also affect its density and stability. 1-Chloro-3-iodobenzene is used in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. Due to the presence of halogens, it may exhibit toxicity and should be handled with appropriate safety precautions.

Formula: C₆H₄ClI

InChI: InChI=1S/C6H4ClI/c7-5-2-1-3-6(8)4-5/h1-4H

InChI key: InChIKey=JMLWXCJXOYDXRN-UHFFFAOYSA-N

SMILES: ClC1=CC(I)=CC=C1

Synonyms:

• 1-Chloro-3-Iodobenzene
• 1-Iodo-3-chlorobenzene
• 3-Chloro-1-iodobenzene
• 3-Chloro-iodobenzene
• 3-Chloroiodobenzene
• 3-Chlorophenyl iodide
• 3-Iodochlorobenzene
• Benzene, 1-chloro-3-iodo-
• NSC 32861
• m-Chlorophenyl iodide
• m-Chloroiodobenzene
• 3-Chloroiodobenzene (stabilized with Copper chip)
• 1-Chloro-3-iodobenzene,98%
• M-IODOCHLOROBENZENE
• 1-Chloro-3-iodopropane 98% stabilized

1-Chloro-3-iodobenzene (stabilized with Copper chip)

CAS: 625-99-0

Formula: C₆H₄ClI

Purity: >97.0%(GC)

Color and Shape: Colorless to Yellow to Green clear liquid

Molecular weight: 238.45

Ref: 3B-C0190

1-Chloro-3-iodobenzene, 98%

CAS: 625-99-0

1-Chloro-3-iodobenzene is used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU referenc

Formula: C₆H₄ClI

Purity: 98%

Color and Shape: Liquid, Clear colorless to pale yellow or pale pink

Molecular weight: 238.45

Ref: 02-A15567

1-Chloro-3-Iodobenzene

CAS: 625-99-0

Formula: C₆H₄ClI

Purity: 98%

Color and Shape: Liquid

Molecular weight: 238.4534

Ref: IN-DA00328C

3-Chloroiodobenzene

CAS: 625-99-0

3-Chloroiodobenzene

Formula: C₆H₄ClI

Purity: 98%

Color and Shape: light yellow to yellow liquid

Molecular weight: 238.45g/mol

Ref: 54-OR30192

1-Chloro-3-iodobenzene

CAS: 625-99-0

Formula: C₆H₄ClI

Molecular weight: 238.45

Ref: 7W-GX1278

1-Chloro-3-iodobenzene, min. 99%

CAS: 625-99-0

Formula: C₆H₄ClI

Purity: min. 99%

Color and Shape: Clear, colorless liquid to pale-yellow liquid

Molecular weight: 238.45

Ref: 08-06-0081

1-Chloro-3-iodobenzene

CAS: 625-99-0

Formula: C₆H₄ClI

Purity: 98% (stabilized with Cu)

Color and Shape: Clear

Molecular weight: 238.45

Ref: 10-F001150

3-​Chloroiodobenzene

Controlled Product

CAS: 625-99-0

Applications 3-​Chloroiodobenzene is used in the synthesis of is a common organic reagent used i the synthesis of a prostacyclin agonist actin in the treatment of pulmonary hypertension.
References Tran, T. et al.: J. Med. Chem., 60, 913 (2017);

Formula: C₃₂H₃₄N₂O₈

Color and Shape: Neat

Molecular weight: 574.621

Ref: TR-C349590

1-Chloro-3-iodobenzene

CAS: 625-99-0

1-Chloro-3-iodobenzene is a chemical compound that is used in the synthesis of ceramics. It is a colorless solid with a melting point of 337℃ and has a molecular weight of 160.161 g/mol. 1-Chloro-3-iodobenzene can be synthesized by reacting zinc powder with ethylmagnesium chloride in the presence of an aluminium catalyst. This reaction produces 1-chloro-3-iodobenzene, which can then be reacted with carbonyl chloride to produce aminocarbonylation products. The chemical compound was first synthesized by Grignard reagents, which are organometallic compounds containing a carbon atom bonded to a magnesium ion. Kinetic studies have shown that 1-chloro-3-iodobenzene reacts with hydroxide ions to form fluorescent products, although it is not reactive towards water or ammonia.

Formula: C₆H₄ClI

Purity: Min. 95%

Molecular weight: 238.45 g/mol

Ref: 3D-FC139705