CAS 62510-46-7

Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, 2-oxide

Description:

Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, 2-oxide, identified by CAS number 62510-46-7, is a heterocyclic organic compound characterized by its complex polycyclic structure. This compound features a fused ring system that includes both pyrazine and azepine moieties, contributing to its unique chemical properties. The presence of multiple rings often results in significant stability and potential biological activity. The "hexahydro" descriptor indicates that the compound has undergone hydrogenation, leading to a saturated structure, while the "2-oxide" suggests the presence of an oxygen atom in the form of an oxide, which can influence its reactivity and solubility. Such compounds are of interest in medicinal chemistry due to their potential pharmacological properties, including neuroactivity and other therapeutic effects. However, specific data regarding its physical properties, such as melting point, boiling point, and solubility, would require empirical investigation or literature reference for precise characterization.

Formula: C₁₈H₂₀N₂O

InChI: InChI=1S/C18H20N2O/c1-20(21)11-10-19-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(19)13-20/h2-9,18H,10-13H2,1H3

InChI key: InChIKey=VVDXWJOYXVNLLQ-UHFFFAOYSA-N

SMILES: CN1(=O)CC2N(C=3C(CC=4C2=CC=CC4)=CC=CC3)CC1

Synonyms:

• 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine 2-oxide
• Dibenzo(c,f)pyrazino(1,2-a)azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, 2-oxide
• Mianserin 2-oxide
• Mianserin-N-oxide

Mianserin N-Oxide

Controlled Product

CAS: 62510-46-7

Formula: C₁₈H₂₀N₂O

Color and Shape: Neat

Molecular weight: 280.36

Ref: 86-MM0147.06

Mianserin N-Oxide

Controlled Product

CAS: 62510-46-7

Applications A metabolite of Mianserin.
References Begg, E., et al.: Br. J. Clin. Pharmacol., 27, 445 (1989), Tybring, G., et al.: Ther. Drug Monit., 17, 516 (1995), Namera, A., et al.: J. Anal. Toxicol. 22, 396 (1998), van Nederkassel, A., et al.: J. Pharm. Biomed. Anal., 32, 233 (2003),

Formula: C₁₈H₂₀N₂O

Color and Shape: Neat

Molecular weight: 280.36

Ref: TR-M341510

Mianserin N-oxide

CAS: 62510-46-7

Mianserin is a drug that belongs to the class of antidepressants. Mianserin N-oxide is an enantiomer of mianserin and has significant cytotoxicity, as it inhibits uptake of phenylephrine in human liver cells. Mianserin N-oxide is a reactive metabolite that is formed by incubation with cytochrome P450 enzymes in the liver and may be responsible for adverse reactions, such as drug interactions and increased sensitivity to drugs. Mianserin N-oxide has been detected in wastewater samples, where it can be used to measure antidepressant use.

Formula: C₁₈H₂₀N₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 280.36 g/mol

Ref: 3D-FM25997

Mianserin N-Oxide

CAS: 62510-46-7

Color and Shape: Neat

Ref: 61-FOR0147.06