CAS 625853-72-7

5-[[4-[2-[5-(2-hydroxyethyl)-2-pyridyl]ethoxy]phenyl]methyl]thiazolidine-2,4-dione

Description:

The chemical substance known as 5-[[4-[2-[5-(2-hydroxyethyl)-2-pyridyl]ethoxy]phenyl]methyl]thiazolidine-2,4-dione, with the CAS number 625853-72-7, is a thiazolidinedione derivative. Thiazolidinediones are a class of compounds known for their role in the treatment of type 2 diabetes, primarily functioning as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ). This particular compound features a thiazolidine ring, which is characteristic of this class, and incorporates a pyridine moiety, contributing to its potential biological activity. The presence of a hydroxyethyl group suggests solubility in polar solvents, while the ethoxy and phenyl groups may enhance lipophilicity and influence its pharmacokinetic properties. The structural complexity indicates potential for diverse interactions with biological targets, making it a candidate for further investigation in medicinal chemistry. Overall, this compound exemplifies the intricate design often found in drug development, aiming to optimize efficacy and minimize side effects.

Formula: C₁₉H₂₀N₂O₄S

InChI: InChI=1/C19H20N2O4S/c22-9-7-14-1-4-15(20-12-14)8-10-25-16-5-2-13(3-6-16)11-17-18(23)21-19(24)26-17/h1-6,12,17,22H,7-11H2,(H,21,23,24)

SMILES: c1cc(CCOc2ccc(cc2)CC2C(=NC(=O)S2)O)ncc1CCO

Hydroxy Pioglitazone (M-VII)

CAS: 625853-72-7

Formula: C₁₉H₂₀N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 372.44

Ref: 4Z-P-1023

Hydroxy Pioglitazone (M-VII)

Controlled Product

CAS: 625853-72-7

Applications A novel metabolite of Pioglitazone (P471000).
References Krieter, P., et al.: Drug Metab. Dispos., 22, 625 (1994), Chilcott, J., et al.: Clin. Ther., 23, 1792 (2001),

Formula: C₁₉H₂₀N₂O₄S

Color and Shape: Neat

Molecular weight: 372.44

Ref: TR-H952060