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CAS 625853-74-9

:

5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl]methyl]-5-hydroxy-thiazolidine-2,4-dione

Description:
The chemical substance known as 5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl]methyl]-5-hydroxy-thiazolidine-2,4-dione, with the CAS number 625853-74-9, is a thiazolidinedione derivative. Thiazolidinediones are a class of compounds known for their role in the treatment of type 2 diabetes, primarily acting as agonists of peroxisome proliferator-activated receptors (PPARs), which play a crucial role in glucose and lipid metabolism. This particular compound features a thiazolidine ring, which is characterized by a five-membered heterocyclic structure containing sulfur and nitrogen. The presence of the ethyl-2-pyridyl group and the phenylmethyl moiety suggests potential interactions with biological targets, enhancing its pharmacological profile. Additionally, the hydroxyl group contributes to its solubility and reactivity, potentially influencing its bioavailability and therapeutic efficacy. Overall, this compound's unique structural features may provide insights into its biological activity and potential applications in medicinal chemistry.
Formula:C19H20N2O4S
InChI:InChI=1/C19H20N2O4S/c1-2-13-3-6-15(20-12-13)9-10-25-16-7-4-14(5-8-16)11-19(24)17(22)21-18(23)26-19/h3-8,12,24H,2,9-11H2,1H3,(H,21,22,23)
InChI key:InChIKey=HDKWBDGQTUQSTO-UHFFFAOYSA-N
SMILES:C(C1(O)C(=O)NC(=O)S1)C2=CC=C(OCCC3=CC=C(CC)C=N3)C=C2
Synonyms:
  • 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-5-hydroxy-
  • 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-5-hydroxy-2,4-thiazolidinedione
  • Pioglitazone EP IMpurity A
  • Pioglitazone EP Impurity A (Pioglitazone 5-Hydroxy Metabolite)
  • Pioglitazone impurities1586
  • Pioglitazone Impurity A(EP)
  • Pioglitazone Impurity A
  • 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]Methyl]-5-hydroxy-
  • 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-5-hydroxy-1,3-thiazolidine-2,4-dione
  • 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-5-hydroxythiazolidine-2,4-dione
  • See more synonyms
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Found 3 products.
  • Pioglitazone EP Impurity A
    TLC
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    Pioglitazone EP Impurity A

    CAS:
    Formula:C19H20N2O4S
    Color and Shape:White To Off-White Solid
    Molecular weight:372.44

    Ref: 4Z-P-1017

    5mg
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    10mg
    3,640.00€
    25mg
    6,674.00€
    50mg
    10,920.00€
    100mg
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  • Pioglitazone EP Impurity A
    Standalix
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    Pioglitazone EP Impurity A

    CAS:
    Formula:C19H20N2O4S
    Molecular weight:372.44

    Ref: ST-EA-CP-P7001

    10mg
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    25mg
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    50mg
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    100mg
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  • 5-Hydroxy pioglitazone
    Biosynth
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    5-Hydroxy pioglitazone

    CAS:
    <p>Pioglitazone is a thiazolidinedione that is used to treat type 2 diabetes. It is an agonist of the peroxisome proliferator-activated receptor gamma (PPARγ), which causes a decrease in insulin resistance and glucose production by the liver, leading to improved glycemic control. Pioglitazone has been shown to have a low potential for drug interactions mediated by cytochrome P450 enzymes. Pioglitazone also has a low potential for drug interactions with other PPARγ agonists because it does not inhibit the enzyme responsible for their metabolism and elimination from the body. Studies have been conducted using liquid chromatography and validated methods to measure levels of pioglitazone and its active metabolites in human plasma following oral administration. The pharmacokinetics of pioglitazone are linear, with an average bioavailability of about 10%. The flow rate of pioglitazone can be determined using mass spectrometry methods.</p>
    Formula:C19H20N2O4S
    Purity:Min. 95%
    Molecular weight:372.44 g/mol

    Ref: 3D-FH24090

    10mg
    863.00€
    25mg
    1,085.00€