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CAS 62587-73-9

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Cefsulodin

Description:
Cefsulodin is a semisynthetic antibiotic belonging to the class of cephalosporins, specifically designed to target Gram-negative bacteria. It is characterized by its broad-spectrum antibacterial activity, particularly effective against Pseudomonas aeruginosa and other resistant strains. Cefsulodin functions by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection and is used in clinical settings to treat various infections, particularly in immunocompromised patients. Its chemical structure includes a beta-lactam ring, which is essential for its antibacterial properties. Cefsulodin is generally well-tolerated, but like other antibiotics, it may cause side effects such as allergic reactions or gastrointestinal disturbances. Due to the emergence of antibiotic resistance, its use is often guided by susceptibility testing. Overall, cefsulodin represents an important therapeutic option in the management of serious infections caused by resistant bacteria.
Formula:C22H20N4O8S2
InChI:InChI=1S/C22H20N4O8S2/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34)/t15-,17-,21-/m1/s1
InChI key:InChIKey=SYLKGLMBLAAGSC-QLVMHMETSA-N
SMILES:C([O-])(=O)C=1N2[C@@]([C@H](NC([C@H](S(=O)(=O)O)C3=CC=CC=C3)=O)C2=O)(SCC1C[N+]=4C=CC(C(N)=O)=CC4)[H]
Synonyms:
  • 3-[(4-Carbamoylpyridinium-1-Yl)Methyl]-8-Oxo-7-{[Phenyl(Sulfo)Acetyl]Amino}-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
  • Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
  • Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-phenylsulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
  • Pyridinium, 4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, [6R-[6α,7β(R*)]]-
  • Cefsulodin
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