CAS 626-05-1

2,6-Dibromopyridine

Description:

2,6-Dibromopyridine is an organic compound characterized by a pyridine ring substituted with two bromine atoms at the 2 and 6 positions. It has the molecular formula C5H3Br2N and is classified as a halogenated heterocyclic compound. This substance typically appears as a colorless to light yellow liquid or solid, depending on the temperature. It is known for its moderate solubility in organic solvents and limited solubility in water. 2,6-Dibromopyridine is utilized in various chemical syntheses, particularly in the production of pharmaceuticals and agrochemicals, due to its reactivity and ability to serve as a building block in organic synthesis. The presence of bromine atoms enhances its electrophilic character, making it a useful intermediate in reactions such as nucleophilic substitutions. Safety precautions are necessary when handling this compound, as it may pose health risks, including skin and eye irritation, and potential environmental hazards. Proper storage and disposal methods should be followed to mitigate any risks associated with its use.

Formula: C₅H₃Br₂N

InChI: InChI=1S/C5H3Br2N/c6-4-2-1-3-5(7)8-4/h1-3H

InChI key: InChIKey=FEYDZHNIIMENOB-UHFFFAOYSA-N

SMILES: BrC=1N=C(Br)C=CC1

Synonyms:

• 2,6-Dibromo Pyridine
• NSC 613
• Pyridine, 2,6-dibromo-
• 2,6-Dibromopyridine

2,6-Dibromopyridine, 98%

CAS: 626-05-1

2,6-Dibromopyridine is used as a tridentate chelating ligand and in the formation of macrocycles containing the terpyridine moiety. It is also used to produce 6-bromo-2-methoxypyridine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some docum

Formula: C₅H₃Br₂N

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White to cream to pale brown to gray

Molecular weight: 236.89

Ref: 02-A15397

2,6-Dibromopyridine

CAS: 626-05-1

Formula: C₅H₃Br₂N

Purity: 97%

Color and Shape: Solid

Molecular weight: 236.894

Ref: 10-F024557

2,6-Dibromopyridine

CAS: 626-05-1

Formula: C₅H₃Br₂N

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.8920

Ref: IN-DA003311

2,6-Dibromopyridine

CAS: 626-05-1

2,6-Dibromopyridine

Formula: C₅H₃Br₂N

Purity: ≥95%

Color and Shape: white to light brown solid

Molecular weight: 236.89201g/mol

Ref: 54-OR28767

2,6-Dibromopyridine

CAS: 626-05-1

Formula: C₅H₃Br₂N

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 236.90

Ref: 7W-GK1540

2,6-Dibromopyridine

CAS: 626-05-1

Formula: C₅H₃Br₂N

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 236.89

Ref: 3B-D1555

2,6-Dibromopyridine

Controlled Product

CAS: 626-05-1

Applications 2,6-Dibromopyridine is used as a starting material to synthesize 2,2’-bipyridines (such as 5-Cyano-1,6-dihydro-6-oxo-[3,4'-bipyridine]-2-carboxylic Acid [C979150]) via a Stille-type cross-coupling reaction. 2,6-Dibromopyridine is also used as a reagent to synthesize pyridylpyrimidine fungicides, compounds that eliminate fungi by cycling copper through the cell membrane, where it reaches toxic levels.
References Hargreaves, S., et al.: Tetrahedron Lett., 41, 1653 (2000); Heller, M. & Schubert, U.: J. Org. Chem., 67, 8269 (2002); Simkovsky, N., et al.: J. Chem. Soc. Perk. Trans. 1, 16, 1847 (2002)

Formula: C₅H₃Br₂N

Color and Shape: Neat

Molecular weight: 236.89

Ref: TR-D425960

2,6-Dibromopyridine

CAS: 626-05-1

2,6-Dibromopyridine (2,6-DBP) is a chemical compound that has been used in the synthesis of other organic compounds. It is an aromatic heterocycle with nitrogen atoms at the 2 and 6 positions. 2,6-DBP is a monosubstituted pyridine derivative that undergoes a palladium-catalyzed coupling reaction with an aryl halide to form pyrazoles. This process can be done unsymmetrically by protonating the 2 position of the dibromopyridine molecule. The presence of serine protease has been shown to promote this reaction by increasing the surface area of the substrate.

Formula: C₅H₃Br₂N

Purity: Min. 98 Area-%

Color and Shape: Off-White Yellow Powder

Molecular weight: 236.89 g/mol

Ref: 3D-FD02560