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CAS 62643-46-3

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20-hydroxyicosanoic acid

Description:
20-Hydroxyicosanoic acid, also known as 20-HETE (20-hydroxyeicosatetraenoic acid), is a bioactive lipid derived from arachidonic acid, which plays a significant role in various physiological processes. It is characterized by its long carbon chain, consisting of 20 carbon atoms with a hydroxyl group at the 20th position. This compound is primarily involved in the regulation of vascular tone, cell proliferation, and inflammation. 20-HETE acts as a signaling molecule in the cardiovascular system, influencing processes such as blood pressure regulation and renal function. It is synthesized through the action of cytochrome P450 enzymes, particularly CYP4A and CYP4F families. The compound exhibits various biological activities, including modulation of ion channels and involvement in the pathophysiology of several diseases, such as hypertension and cancer. Due to its potent effects, 20-HETE is a subject of interest in pharmacological research, particularly in the development of therapeutic agents targeting cardiovascular and inflammatory disorders.
Formula:C20H40O3
InChI:InChI=1/C20H40O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h21H,1-19H2,(H,22,23)
SMILES:C(CCCCCCCCCC(=O)O)CCCCCCCCCO
Synonyms:
  • Eicosanoic Acid, 20-Hydroxy-
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