CAS 6265-73-2

N-(2-Hydroxyethyl)nicotinamide

Description:

N-(2-Hydroxyethyl)nicotinamide, also known as 2-hydroxyethyl niacinamide, is a derivative of niacinamide (nicotinamide) that features a hydroxyethyl group. This compound is characterized by its white to off-white crystalline appearance and is soluble in water and alcohol, making it suitable for various applications in pharmaceuticals and cosmetics. It exhibits properties that can enhance skin hydration, improve barrier function, and provide anti-inflammatory effects, which makes it a popular ingredient in skincare formulations. Additionally, it may play a role in cellular metabolism and has been studied for its potential benefits in treating skin conditions such as acne and hyperpigmentation. The compound is generally considered safe for topical use, but like any chemical, it should be handled with care, following appropriate safety guidelines. Its stability and compatibility with other ingredients in formulations are also important considerations for effective use in various applications.

Formula: C₈H₁₀N₂O₂

InChI: InChI=1S/C8H10N2O2/c11-5-4-10-8(12)7-2-1-3-9-6-7/h1-3,6,11H,4-5H2,(H,10,12)

InChI key: InChIKey=SJZLOWYUGKIWAK-UHFFFAOYSA-N

SMILES: C(NCCO)(=O)C=1C=CC=NC1

Synonyms:

• 3-(2-Hydroxyethyl)carbamoylpyridine
• 3-pyridinecarboxamide, N-(2-hydroxyethyl)-
• Hydroxyethyl nicotinamide
• N-(2-Hydroxyethyl)-3-Pyridinecarboxamide
• N-(2-hydroxyethyl)nicotinamide
• N-Nicotinoyl-2-aminoethanol
• N-Nicotinoylethanolamine
• NSC 33142
• Nicotinamide, N-(2-hydroxyethyl)-
• Sg 86

Nicorandil amide

CAS: 6265-73-2

Nicorandil amide

Color and Shape: White. To. Light Yellow

Ref: 47-1106

Nicorandil impurity standard

CAS: 59-67-6, 6265-73-2

Nicorandil impurity standard

Color and Shape: Light Yellow

Ref: 47-1237

N-(2-Hydroxyethyl)nitotinamide

CAS: 6265-73-2

Formula: C₈H₁₀N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 166.1772

Ref: IN-DA00EIC4

N-(2-Hydroxyethyl)nicotinamide

CAS: 6265-73-2

N-(2-Hydroxyethyl)nicotinamide

Purity: 97%

Molecular weight: 166.18g/mol

Ref: 54-OR1002087

Nicorandil EP Impurity B

CAS: 6265-73-2

Formula: C₈H₁₀N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 166.18

Ref: 4Z-N-054

Nicorandil Tetramer

CAS: 6265-73-2

Formula: C₃₂H₃₃N₉O₇

Color and Shape: White To Off-White Solid

Molecular weight: 655.67

Ref: 4Z-N-0540

Nicorandil Impurity 34

CAS: 6265-73-2

Formula: C₈H₉N₃O₃

Color and Shape: White To Off-White Solid

Molecular weight: 195.18

Ref: 4Z-N-0543

N-(2-Hydroxyethyl)nicotinamide-d4

Controlled Product

CAS: 6265-73-2

Applications N-(2-Hydroxyethyl)nitotinamide-d4 is labelled N-(2-Hydroxyethyl)nitotinamide (H942365), an intermediate used to prepare oxadiazole oxide derivatives as vasodilators. It is also a derivative of Nicorandil (N398500) which is an antiaginal.
References Boschi, D., et al.: Bioorg. Med. Chem., 8, 1727 (2000); Nagai, H., et al.: Chem. Pharm. Bull., 32, 1063 (1984); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)

Formula: C₈H₆D₄N₂O₂

Color and Shape: Neat

Molecular weight: 170.2

Ref: TR-H942367

N-(2-Hydroxyethyl)nicotinamide

Controlled Product

CAS: 6265-73-2

Applications N-(2-Hydroxyethyl)nitotinamide is an intermediate used to prepare oxadiazole oxide derivatives as vasodilators. It is also a derivative of Nicorandil (N398500) which is an antiaginal.
References Boschi, D., et al.: Bioorg. Med. Chem., 8, 1727 (2000); Nagai, H., et al.: Chem. Pharm. Bull., 32, 1063 (1984); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)

Formula: C₈H₁₀N₂O₂

Color and Shape: Neat

Molecular weight: 166.18

Ref: TR-H942365

Nicorandil EP Impurity B

CAS: 6265-73-2

Formula: C₈H₁₀N₂O₂

Molecular weight: 166.18

Ref: ST-EA-CP-N34002

N-(2-Hydroxyethyl)nitotinamide

CAS: 6265-73-2

Formula: C₈H₁₀N₂O₂

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 166.18

Ref: 10-F078223