CAS 62666-20-0: Progabide
Description:Progabide, with the CAS number 62666-20-0, is a chemical compound that functions primarily as an anticonvulsant and has been investigated for its potential use in treating epilepsy and other neurological disorders. It is a derivative of gamma-aminobutyric acid (GABA), which is a key neurotransmitter in the central nervous system. Progabide acts as a GABA receptor agonist, enhancing the inhibitory effects of GABA and thereby helping to stabilize neuronal activity. The compound is typically characterized by its ability to cross the blood-brain barrier, which is crucial for its therapeutic effects. Progabide is known for its relatively low toxicity profile, but like many medications, it may have side effects, including sedation or dizziness. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are important for determining its efficacy and safety in clinical use. Overall, progabide represents a significant area of interest in neuropharmacology, particularly for its role in managing seizure disorders.
Formula:C17H16ClFN2O2
InChI:InChI=1S/C17H16ClFN2O2/c18-12-5-3-11(4-6-12)17(21-9-1-2-16(20)23)14-10-13(19)7-8-15(14)22/h3-8,10,22H,1-2,9H2,(H2,20,23)
InChI key:InChIKey=IBALRBWGSVJPAP-UHFFFAOYSA-N
SMILES:O=C(N)CCCN=C(C1=CC=C(Cl)C=C1)C2=CC(F)=CC=C2O
- Synonyms:
- 4-[[(4-Chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]butanamide
- Gabren
- Gabrene
- Halogabide
- Progabid
- Progabida
- Progabide
- Sl 76-002
- Sl 76002
- 62666-20-0
- See more synonyms
- 4-{[(E)-(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylidene]amino}butanamide
- Butanamide, 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]-
- 263-679-4
- 4-(alpha-(p-Chlorophenyl)-5-fluoro-2-hydroxybenzylideneamino)butyramide
- 4-{[(E)-(4-Chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino}butanamide
- 4-[[a-(p-Chlorophenyl)-5-fluorosalicylidene]amino]butyramide
- Butyramide, 4-(alpha-(p-chlorophenyl)-5-fluoro-2-hydroxybenzylideneamino)-
- 4-[[a-(p-Chlorophenyl)-5-fluoro-2-hydroxybenzylidene]amino]butyramide
