CAS 62666-20-0

Progabide

Description:

Progabide, with the CAS number 62666-20-0, is a chemical compound that functions primarily as an anticonvulsant and has been investigated for its potential use in treating epilepsy and other neurological disorders. It is a derivative of gamma-aminobutyric acid (GABA), which is a key neurotransmitter in the central nervous system. Progabide acts as a GABA receptor agonist, enhancing the inhibitory effects of GABA and thereby helping to stabilize neuronal activity. The compound is typically characterized by its ability to cross the blood-brain barrier, which is crucial for its therapeutic effects. Progabide is known for its relatively low toxicity profile, but like many medications, it may have side effects, including sedation or dizziness. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are important for determining its efficacy and safety in clinical use. Overall, progabide represents a significant area of interest in neuropharmacology, particularly for its role in managing seizure disorders.

Formula: C₁₇H₁₆ClFN₂O₂

InChI: InChI=1S/C17H16ClFN2O2/c18-12-5-3-11(4-6-12)17(21-9-1-2-16(20)23)14-10-13(19)7-8-15(14)22/h3-8,10,22H,1-2,9H2,(H2,20,23)

InChI key: InChIKey=IBALRBWGSVJPAP-UHFFFAOYSA-N

SMILES: C(=NCCCC(N)=O)(C1=C(O)C=CC(F)=C1)C2=CC=C(Cl)C=C2

Synonyms:

• 4-[[(4-Chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]butanamide
• Gabren
• Gabrene
• Halogabide
• Progabid
• Progabida
• Progabide
• Sl 76-002
• Sl 76002
• 62666-20-0
• 4-{[(E)-(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylidene]amino}butanamide
• Butanamide, 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]-
• 263-679-4
• 4-(alpha-(p-Chlorophenyl)-5-fluoro-2-hydroxybenzylideneamino)butyramide
• 4-{[(E)-(4-Chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino}butanamide
• 4-[[a-(p-Chlorophenyl)-5-fluorosalicylidene]amino]butyramide
• Butyramide, 4-(alpha-(p-chlorophenyl)-5-fluoro-2-hydroxybenzylideneamino)-

Progabide

CAS: 62666-20-0

Formula: C₁₇H₁₆ClFN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 334.7725

Ref: IN-DA00EAXL

Progabide

CAS: 62666-20-0

Progabide

Purity: ≥98%

Molecular weight: 334.77g/mol

Ref: 54-BUP10125

Halogabide

CAS: 62666-20-0

Formula: C₁₇H₁₆ClFN₂O₂

Molecular weight: 334.77

Ref: 7W-GP0633

Progabide

Controlled Product

CAS: 62666-20-0

Applications Progabide is a gamma-aminobutyric acid (GABA) antagonist with antiepileptic activity.
References Johno, I., et al.: J. Pharm. Sci., 71, 633 (1982), Shestakova., et al.: Bull. Exp. Biol. Med., 137, 255 (2004),

Formula: C₁₇H₁₆ClFN₂O₂

Color and Shape: Neat

Molecular weight: 334.77

Ref: TR-P755350

Progabide

CAS: 62666-20-0

Analogue of GABA; GABA receptor agonist used in epilepsy

Formula: C₁₇H₁₆ClFN₂O₂

Purity: Min. 95%

Color and Shape: Beige Powder

Molecular weight: 334.77 g/mol

Ref: 3D-FP103146

Progabide

CAS: 62666-20-0

Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.

Formula: C₁₇H₁₆ClFN₂O₂

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 334.77

Ref: TM-T16581