CAS 62669-70-9

Rhodamine 123

Description:

Rhodamine 123 is a synthetic dye belonging to the rhodamine family, characterized by its vibrant fluorescent properties. It is commonly used as a tracer in various biological and chemical applications due to its ability to emit bright green fluorescence when excited by light. The compound has a molecular formula of C27H31ClN2O3 and features a xanthene structure, which contributes to its stability and solubility in organic solvents. Rhodamine 123 is often utilized in cell biology to study mitochondrial function, as it selectively accumulates in mitochondria, allowing researchers to visualize and assess mitochondrial activity and health. Additionally, it has applications in photodynamic therapy and as a fluorescent marker in various analytical techniques. However, caution is advised when handling this compound, as it can be toxic and may pose environmental hazards. Its stability under different pH conditions and its photostability make it a valuable tool in both research and industrial settings.

Formula: C₂₁H₁₇N₂O₃·Cl

InChI: InChI=1S/C21H17N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11H,22-23H2,1H3;1H/q+1;/p-1

InChI key: InChIKey=TUFFYSFVSYUHPA-UHFFFAOYSA-M

SMILES: C(OC)(=O)C1=C(C=2C3=C([O+]=C4C2C=CC(N)=C4)C=C(N)C=C3)C=CC=C1.[Cl-]

Synonyms:

• 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monohydrochloride
• 3,6-Diamino-9-[2-(Methoxycarbonyl)Phenyl]Xanthenium Chloride
• 6-amino-9-[2-(methoxycarbonyl)phenyl]-3H-xanthen-3-iminium chloride
• Benzoic acid, 2-(6-amino-3-imino-3H-xanthen-9-yl)-, methyl ester, monohydrochloride
• R 22420
• R 302
• Rh 123
• Rhodamine 123
• Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
• Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride (1:1)
• 3,6-Diamino-9-(2-(methoxycarbonyl)phenyl)xanthylium chloride

Rhodamine 123

CAS: 62669-70-9

Formula: C₂₁H₁₇ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 380.8243

Ref: IN-DA00IB2C

3,6-Diamino-9-(2-(Methoxycarbonyl)Phenyl)Xanthylium Chloride

CAS: 62669-70-9

3,6-Diamino-9-(2-(Methoxycarbonyl)Phenyl)Xanthylium Chloride

Purity: 98%

Molecular weight: 380.82g/mol

Ref: 54-OR1022938

Rhodamine 123

CAS: 62669-70-9

Rhodamine 123

Purity: ≥98%

Molecular weight: 380.83g/mol

Ref: 54-BUP06103

Rhodamine 123

CAS: 62669-70-9

Formula: C₂₁H₁₇ClN₂O₃

Color and Shape: Brown to red powder

Molecular weight: 380.8

Ref: 7W-GT3585

Rhodamine 123

CAS: 62669-70-9

Rhodamine 123 is a fluorescent dye (λex=503 nm, λem=527 nm).

Formula: C₂₁H₁₇ClN₂O₃

Purity: 99.23% - 99.95%

Color and Shape: Red To Brown Powder

Molecular weight: 380.83

Ref: TM-T16743

Rhodamine-123

CAS: 62669-70-9

Applications Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).
References Yumoto, R., et al.: J. Pharmacol. Exp. Ther., 289, 149 (1999), Romiti, N., et al.: Toxicol. Appl. Pharmacol., 183, 83 (2002), Mizuno, N., et al.: Pharmacol. Rev., 559, 425 (2003), del Amo, E., et al.: Eur. J. Pharm. Sci., 36, 200 (2009),

Formula: C₂₁H₁₆N₂O₃·ClH

Color and Shape: Neat

Molecular weight: 380.82

Ref: TR-R318585

Rhodamine 123

CAS: 62669-70-9

Purity: 97%

Molecular weight: 380.09

Ref: 10-F979221

Rhodamine-123 6-C2-Maleimide Sulfate Salt

Controlled Product

CAS: 62669-70-9

Formula: C₂₈H₂₃N₄O₆·HO₄S

Color and Shape: Neat

Molecular weight: 608.576

Ref: TR-R318600