CAS 62673-31-8

benzyl(bromo)zinc

Description:

Benzyl(bromo)zinc, with the CAS number 62673-31-8, is an organozinc compound characterized by the presence of a benzyl group and a bromine atom coordinated to a zinc center. This compound typically appears as a colorless to light yellow liquid or solid, depending on its form and purity. It is known for its reactivity, particularly in organic synthesis, where it serves as a versatile reagent in cross-coupling reactions, such as the Suzuki and Negishi reactions, facilitating the formation of carbon-carbon bonds. Benzyl(bromo)zinc is sensitive to moisture and air, necessitating careful handling under inert atmospheres to prevent decomposition or unwanted reactions. Its applications extend to the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Additionally, the compound's properties, such as solubility in organic solvents and its ability to act as a nucleophile, make it valuable in synthetic organic chemistry. Safety precautions are essential when working with this compound due to its potential hazards, including toxicity and reactivity.

Formula: C₇H₇BrZn

InChI: InChI=1/C7H7.BrH.Zn/c1-7-5-3-2-4-6-7;;/h2-6H,1H2;1H;/q;;+1/p-1/rC7H7BrZn/c8-9-6-7-4-2-1-3-5-7/h1-5H,6H2

SMILES: C=C1[CH]C=CC=C1.Br.[Zn]

Synonyms:

• Benzylzinc bromide

Benzylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles

CAS: 62673-31-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₇BrZn

Molecular weight: 236.42

Ref: 02-H58014

Benzylzinc bromide 0.5 M in Tetrahydrofuran

Controlled Product

CAS: 62673-31-8

Benzylzinc bromide is a mild reducing agent that is used in organic synthesis. It is a n-oxide and syncytial virus inhibitor and can be used to treat cancer. The reaction mechanism of benzylzinc bromide involves the formation of an intramolecular hydrogen bond between hydrogen in the alpha position and the bromine atom. This bond is cleaved by an electron from another molecule, which causes the release of hydrogen gas. The product formed is benzyl alcohol, which reacts with sodium hydroxide to form sodium benzoate. In some cases, this reaction leads to a second one with the sodium benzoate, forming benzylbromide and sodium hydroxide. Benzylzinc bromide has been shown to inhibit lipid kinase in cells infected by HIV-1, making it possible for scientists to better understand how HIV-1 enters cells. It also inhibits Toll-like receptor 1, which plays a key role in

Formula: C₇H₇BrZn

Purity: Min. 95%

Molecular weight: 236.42 g/mol

Ref: 3D-MCA67331