CAS 6270-46-8

5-Amino-6-methyl-2,4(1H,3H)-pyrimidinedione

Description:

5-Amino-6-methyl-2,4(1H,3H)-pyrimidinedione, also known as 5-amino-6-methyluracil, is a heterocyclic organic compound characterized by its pyrimidine ring structure, which contains two carbonyl groups and an amino group. This compound is typically a white to off-white crystalline solid, soluble in water and polar organic solvents, reflecting its polar functional groups. It exhibits basic properties due to the presence of the amino group, allowing it to participate in various chemical reactions, including nucleophilic substitutions. The compound is of interest in medicinal chemistry and biochemistry, particularly for its potential role as an intermediate in the synthesis of pharmaceuticals and as a building block in nucleic acid analogs. Its molecular structure allows for hydrogen bonding, which can influence its biological activity and interactions with other molecules. Additionally, it may exhibit tautomerism, contributing to its reactivity and stability under different conditions. Overall, 5-amino-6-methyl-2,4(1H,3H)-pyrimidinedione is a versatile compound with significant implications in chemical and biological research.

Formula: C₅H₇N₃O₂

InChI: InChI=1S/C5H7N3O2/c1-2-3(6)4(9)8-5(10)7-2/h6H2,1H3,(H2,7,8,9,10)

InChI key: InChIKey=FNSSATCDUXTALE-UHFFFAOYSA-N

SMILES: NC1=C(C)NC(=O)NC1=O

Synonyms:

• 2,4(1H,3H)-Pyrimidinedione, 5-amino-6-methyl-
• 5-Amino-6-methyl-2,4(1H,3H)-pyrimidinedione
• 5-amino-6-methylpyrimidine-2,4(1H,3H)-dione
• NSC 35527
• Uracil, 5-amino-6-methyl-
• 5-Amino-6-methyluracil

5-AMINO-2,4-DIHYDROXY-6-METHYLPYRIMIDINE

CAS: 6270-46-8

Formula: C₅H₇N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 141.1280

Ref: IN-DA00EAWU

5-Amino-6-methylpyrimidine-2,4-diol

CAS: 6270-46-8

5-Amino-6-methylpyrimidine-2,4-diol

Purity: 98%

Molecular weight: 141.13g/mol

Ref: 54-OR89741

5-Amino-6-methyl-pyrimidine-2,4-diol

CAS: 6270-46-8

Formula: C₅H₇N₃O₂

Purity: 98%

Molecular weight: 141.13

Ref: 10-F058195

5-Amino-6-methyl-pyrimidine-2,4-diol

CAS: 6270-46-8

5-Amino-6-methyl-pyrimidine-2,4-diol is a tautomer of 5-Aminouracil. It is an antiradical agent that has been shown to have hydroxyl radical scavenging activity in the presence of peroxide. The mechanism of the reaction involves the formation of a hydrated form of 5-amino-6-methylpyrimidine 2,4-diol, which reacts with the peroxide to form a stable product. The hydration step is required for this reaction to occur and may be rate limiting. The measurements obtained from nmr spectra are consistent with this mechanism. 5 aminouracil has been shown to inhibit growth and DNA synthesis in tumor cells in vitro.

Formula: C₅H₇N₃O₂

Purity: Min. 95%

Molecular weight: 141.13 g/mol

Ref: 3D-GAA27046